Preprint Case Report Version 1 Preserved in Portico This version is not peer-reviewed

Persistent Ependymal Tumor Arising from an Immature Ovarian Teratoma: A Rare Case

Version 1 : Received: 4 October 2020 / Approved: 5 October 2020 / Online: 5 October 2020 (13:43:44 CEST)

How to cite: Afzal, A.; Lu, R.; Asadbeigi, S.; Fung, K.; Peterson, J. Persistent Ependymal Tumor Arising from an Immature Ovarian Teratoma: A Rare Case. Preprints 2020, 2020100081 (doi: 10.20944/preprints202010.0081.v1). Afzal, A.; Lu, R.; Asadbeigi, S.; Fung, K.; Peterson, J. Persistent Ependymal Tumor Arising from an Immature Ovarian Teratoma: A Rare Case. Preprints 2020, 2020100081 (doi: 10.20944/preprints202010.0081.v1).

Abstract

Primary ovarian ependymoma is a rare neuroectodermal neoplasm that can arise from immature ovarian teratoma. Due to the paucity of this entity, a complete molecular analysis of these tumors has not been done, thus creating a challenge for finding an effective and safe therapeutic treatment. In limited literature, patient with primary ovarian ependymoma showed various responses to an array of individualized therapies ranging from surgeries and chemotherapies. Here, we present a 38-year-old female with persistent ovarian ependymoma with molecular profile similar to traditional central nervous system ependymoma that is irresponsive to multiple cytoreduction and clinical experimental therapies. Therefore, a prompt recognition and reporting of this entity can greatly aid in expanding the understanding and standardization of therapies for this neoplasm.

Subject Areas

Ependymoma; teratoma; ovarian; immature teratoma

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