Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

A New Perspective on Covid-19 Treatment: When a Paradigm Changes in Infectiology Become Necessary against an Emerging Virus as the SARS-Cov2

Version 1 : Received: 22 September 2020 / Approved: 24 September 2020 / Online: 24 September 2020 (03:40:34 CEST)

How to cite: Ouedraogo, L.S.P.; Apeti, S.; Ouedraogo, D. A New Perspective on Covid-19 Treatment: When a Paradigm Changes in Infectiology Become Necessary against an Emerging Virus as the SARS-Cov2 . Preprints 2020, 2020090561. https://doi.org/10.20944/preprints202009.0561.v1 Ouedraogo, L.S.P.; Apeti, S.; Ouedraogo, D. A New Perspective on Covid-19 Treatment: When a Paradigm Changes in Infectiology Become Necessary against an Emerging Virus as the SARS-Cov2 . Preprints 2020, 2020090561. https://doi.org/10.20944/preprints202009.0561.v1

Abstract

Background & Aims: The covid19 is a world changing challenge. Furthermore, this disease challenges our capacities to change our point of view in the domain of infectiology, immunology and global public health. Many trials try some drug such as antiviral (lopinavir, remdesivir) interferon, and the chloroquine. Unfortunately, all approach is not really convincing at this time. We are proposing another approach on this issue. In infectiology there are two protagonists : the host and its immune system versus pathogens and its virulence. Our approach focuses on an intervention on the host’s immune system and how stimulate and modulate its reactions. Methods: We searched on PubMed and Google Scholar databases for French and English-language studies, without a limit of date of publications, for randomized clinical trials, meta-analyses, reviews, systematic reviews, observational studies, case report. We performed a review on the field of immunology enhancements by nutrients use. Results: We identified groups of vitamins (D and C), oligo-elements (magnesium, zinc, selenium) and nutrition advice which enhance immune system response. Indeed, these supplements have some proved properties in modulating and stimulating the immune system. For example, a recent study demonstrates that vitamin D deficiency is linked with the severity of covid19. Majority of the population has a deficiency in these elements. According to this, we propose a therapeutic protocol using these elements to reach an efficient therapy against covid19 by enhancing host’s immune system. Conclusion: Due to this serious pandemic, any solutions must not be disregarded. The nutrition way is an entire part of the solution.

Keywords

covid19; immunostimulant; immunomodulator; vitamin D; vitamin C; zinc

Subject

Biology and Life Sciences, Virology

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