Version 1
: Received: 22 September 2020 / Approved: 23 September 2020 / Online: 23 September 2020 (17:44:21 CEST)
How to cite:
Tomasa-Irriguible, T.; Bielsa-Berrocal, L. Up to 40% of COVID-19 Critically Ill Patients Have Vitamin D Deficiency. Preprints2020, 2020090555. https://doi.org/10.20944/preprints202009.0555.v1
Tomasa-Irriguible, T.; Bielsa-Berrocal, L. Up to 40% of COVID-19 Critically Ill Patients Have Vitamin D Deficiency. Preprints 2020, 2020090555. https://doi.org/10.20944/preprints202009.0555.v1
Tomasa-Irriguible, T.; Bielsa-Berrocal, L. Up to 40% of COVID-19 Critically Ill Patients Have Vitamin D Deficiency. Preprints2020, 2020090555. https://doi.org/10.20944/preprints202009.0555.v1
APA Style
Tomasa-Irriguible, T., & Bielsa-Berrocal, L. (2020). Up to 40% of COVID-19 Critically Ill Patients Have Vitamin D Deficiency. Preprints. https://doi.org/10.20944/preprints202009.0555.v1
Chicago/Turabian Style
Tomasa-Irriguible, T. and Lara Bielsa-Berrocal. 2020 "Up to 40% of COVID-19 Critically Ill Patients Have Vitamin D Deficiency" Preprints. https://doi.org/10.20944/preprints202009.0555.v1
Abstract
Background: Coronavirus disease (COVID-19) has caused more than 745,000 deaths worldwide. Vitamin D has been identified as a potential strategy to prevent or treat this disease. The purpose of the study was to measure vitamin D at hospital admission of COVID-19; Methods: We included critically ill patients with the polymerase chain reaction positive test for COVID-19, from March to April, 2020. Statistical significance was defined as P < .05. All tests were 2-tailed; Results: A total of 35 patients (median age, 60 years; 26 [74.3%] male) were included. Vitamin D levels were categorized as deficient for 14 participants (40%). Vitamin D deficiency was associated with vitamin A (P= 0.003) and Zinc (P= 0.019) deficiency and lower levels of albumin (P= 0.026) and prealbumin (P= 0.009). Overall, none of the studied variables were associated with vitamin D status: mortality, intensive care unit (ICU) or hospital stay, necessity of vasoactive agents, intubation, prone position, C reactive protein (CRP), Dimer-D, Interleukin 6 levels (IL-6), ferritin levels, or bacterial superinfection; Conclusions: In this single-center, retrospective cohort study, deficient vitamin D status was found in 40% in COVID-19 critically ill patients. However, deficient vitamin D status was not associated with inflammation or outcome.
Keywords
SARS-CoV-2; covid-19; vitamins
Subject
Medicine and Pharmacology, Dietetics and Nutrition
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
