Preprint Brief Report Version 1 Preserved in Portico This version is not peer-reviewed

Up to 40% of COVID-19 Critically Ill Patients Have Vitamin D Deficiency

Version 1 : Received: 22 September 2020 / Approved: 23 September 2020 / Online: 23 September 2020 (17:44:21 CEST)

How to cite: Tomasa-Irriguible, T.; Bielsa-Berrocal, L. Up to 40% of COVID-19 Critically Ill Patients Have Vitamin D Deficiency. Preprints 2020, 2020090555 (doi: 10.20944/preprints202009.0555.v1). Tomasa-Irriguible, T.; Bielsa-Berrocal, L. Up to 40% of COVID-19 Critically Ill Patients Have Vitamin D Deficiency. Preprints 2020, 2020090555 (doi: 10.20944/preprints202009.0555.v1).

Abstract

Background: Coronavirus disease (COVID-19) has caused more than 745,000 deaths worldwide. Vitamin D has been identified as a potential strategy to prevent or treat this disease. The purpose of the study was to measure vitamin D at hospital admission of COVID-19; Methods: We included critically ill patients with the polymerase chain reaction positive test for COVID-19, from March to April, 2020. Statistical significance was defined as P < .05. All tests were 2-tailed; Results: A total of 35 patients (median age, 60 years; 26 [74.3%] male) were included. Vitamin D levels were categorized as deficient for 14 participants (40%). Vitamin D deficiency was associated with vitamin A (P= 0.003) and Zinc (P= 0.019) deficiency and lower levels of albumin (P= 0.026) and prealbumin (P= 0.009). Overall, none of the studied variables were associated with vitamin D status: mortality, intensive care unit (ICU) or hospital stay, necessity of vasoactive agents, intubation, prone position, C reactive protein (CRP), Dimer-D, Interleukin 6 levels (IL-6), ferritin levels, or bacterial superinfection; Conclusions: In this single-center, retrospective cohort study, deficient vitamin D status was found in 40% in COVID-19 critically ill patients. However, deficient vitamin D status was not associated with inflammation or outcome.

Subject Areas

SARS-CoV-2; covid-19; vitamins

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our diversity statement.

Leave a public comment
Send a private comment to the author(s)
Views 0
Downloads 0
Comments 0
Metrics 0


×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.