Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Analysis of the Primary Presenting Symptoms and Hematological Findings of COVID-19 Patients in Bangladesh

Version 1 : Received: 21 June 2020 / Approved: 21 June 2020 / Online: 21 June 2020 (14:47:03 CEST)

How to cite: Mohiuddin Chowdhury, A.T.M.; Karim, M.R.; Mehedi, H.H.; Shahbaz, M.; Chowdhury, M.W.; Dan, G.; He, S. Analysis of the Primary Presenting Symptoms and Hematological Findings of COVID-19 Patients in Bangladesh. Preprints 2020, 2020060275 (doi: 10.20944/preprints202006.0275.v1). Mohiuddin Chowdhury, A.T.M.; Karim, M.R.; Mehedi, H.H.; Shahbaz, M.; Chowdhury, M.W.; Dan, G.; He, S. Analysis of the Primary Presenting Symptoms and Hematological Findings of COVID-19 Patients in Bangladesh. Preprints 2020, 2020060275 (doi: 10.20944/preprints202006.0275.v1).

Abstract

Objective: SARS-Cov-2 infection or COVID-19 is a global pandemic. From the time of identification to till, multiple clinical symptoms and parameters have been identified by the researchers of various countries and regions regarding the diagnosis and presentations of COVID-19 disease. In this manuscript, we investigated the primary symptoms and basic hematological presentations of SARS-CoV-2 infection among the Bangladeshi patients. Methodology: We have collected the disease history of mild to moderate degree of COVID-19 patients; hematological and biochemical on admission reports of moderate degree COVID-19 patients. All of them were tested positive for SARS-CoV-2 by RT-PCR in different institutes in Bangladesh. Results: According to this study though COVID-19 patients in Bangladesh commonly presented with fever, cough, fatigue, shortness of breath, and sore throat, but symptoms like myalgia, diarrhea, skin rash, headache, Abdominal pain/cramp, nausea, vomiting, restlessness, and a higher temperature of >1000F have a greater presentation rate and more frequent than other published studies. CRP and Prothrombin time was found to increase in all the patients. Serum ferritin, ESR, SGPT, and D-Dimer were found increased among 53.85%, 80.43, 44%, and 25% patients respectively. 17.39% of the patients had leukocytosis and neutrophilia. 28.26% of patients presented with lymphocytopenia. 62.52% of patients had mild erythrocytopenia. Conclusion: Despite some similarities, our study has evaluated a different expression in presenting symptoms in the case of COVID-19 patients in Bangladesh. CRP, Prothrombin time, serum ferritin, ESR, SGPT, D-Dimer, erythrocytopenia, and lymphocytopenia can be initial diagnostic hematological findings and assessment for prognosis COVID-19 disease. Also, gender variations have a different scenario of clinical and laboratory appearance in this region.

Subject Areas

SARS-CoV-2; COVID-19; real-time RT-PCR; COVID-19 symptoms; COVID-19 hematological findings; Bangladesh

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our diversity statement.

Leave a public comment
Send a private comment to the author(s)
Views 0
Downloads 0
Comments 0
Metrics 0


×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.