From Extracellular Vesicles to Global Environment: A Cosmopolite SARS-Cov-2 Virus

Veronika Kralj-Iglič; Raja Dahmane; Tjaša Griessler Bulc; Polonca Trebše; Saba Battelino; Mojca Bavcon Kralj; Metka Benčina; Klemen Bohinc; Darja Božič; Mojca Debeljak; Drago Dolinar; Aleš Iglič; Darja Istenič; Zala Jan; Monika Jenko; Marko Jeran; Gregor Jereb; Mojca Jevšnik; Aleksandra Krivograd Klemenčič; Tomaž Lampe; Irina Milisav; Andreea Oarga-Mulec; Andrej Ovca; Borut Poljšak; Franja Prosenc; Anna Romolo; Nina Resnik; Robert Sotler; Anja Šoštarič; Vid Šuštar; Urška Šunta; Urška Štibler; Bojana Uršič; Domen Vozel

doi:10.20944/preprints202005.0518.v1

How to cite: Kralj-Iglič, V.; Dahmane, R.; Griessler Bulc, T.; Trebše, P.; Battelino, S.; Bavcon Kralj, M.; Benčina, M.; Bohinc, K.; Božič, D.; Debeljak, M.; Dolinar, D.; Iglič, A.; Istenič, D.; Jan, Z.; Jenko, M.; Jeran, M.; Jereb, G.; Jevšnik, M.; Krivograd Klemenčič, A.; Lampe, T.; Milisav, I.; Oarga-Mulec, A.; Ovca, A.; Poljšak, B.; Prosenc, F.; Romolo, A.; Resnik, N.; Sotler, R.; Šoštarič, A.; Šuštar, V.; Šunta, U.; Štibler, U.; Uršič, B.; Vozel, D. From Extracellular Vesicles to Global Environment: A Cosmopolite SARS-Cov-2 Virus . Preprints 2020, 2020050518. https://doi.org/10.20944/preprints202005.0518.v1. Kralj-Iglič, V.; Dahmane, R.; Griessler Bulc, T.; Trebše, P.; Battelino, S.; Bavcon Kralj, M.; Benčina, M.; Bohinc, K.; Božič, D.; Debeljak, M.; Dolinar, D.; Iglič, A.; Istenič, D.; Jan, Z.; Jenko, M.; Jeran, M.; Jereb, G.; Jevšnik, M.; Krivograd Klemenčič, A.; Lampe, T.; Milisav, I.; Oarga-Mulec, A.; Ovca, A.; Poljšak, B.; Prosenc, F.; Romolo, A.; Resnik, N.; Sotler, R.; Šoštarič, A.; Šuštar, V.; Šunta, U.; Štibler, U.; Uršič, B.; Vozel, D. From Extracellular Vesicles to Global Environment: A Cosmopolite SARS-Cov-2 Virus . Preprints 2020, 2020050518. https://doi.org/10.20944/preprints202005.0518.v1.

Abstract

Within the micro and nano world, tiny membrane-enclosed bits of material are more or less free to move and act as communication tools within cells, between cells, between different tissues and between organisms in global environment. Based on the mechanism of membrane budding and vesiculation that includes all types of cells, in this review, we attempted to present a review on SARS-CoV-2 virus actions in compartments of different scales (cells and their surroundings, tissues, organisms and society). Interactions of the virus with cells on a molecular level, with neural system, endothelium, hematopoietic system, gastrointestinal system and genitourinary system. Transmission route between organisms and between mother and fetus are considered. Also, transmission of virus through contact with materials and with environment, the suggested measures to prevent contamination with the virus and to support the organism against the disease are given.

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From Extracellular Vesicles to Global Environment: A Cosmopolite SARS-Cov-2 Virus

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