Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Community Research Amid COVID-19 Pandemic: Genomics Analysis of SARS-CoV-2 over Public GALAXY server

Version 1 : Received: 19 May 2020 / Approved: 21 May 2020 / Online: 21 May 2020 (09:57:42 CEST)

How to cite: Kumar, A.; Bangash, A.H.; Gruening, B. Community Research Amid COVID-19 Pandemic: Genomics Analysis of SARS-CoV-2 over Public GALAXY server. Preprints 2020, 2020050343 (doi: 10.20944/preprints202005.0343.v1). Kumar, A.; Bangash, A.H.; Gruening, B. Community Research Amid COVID-19 Pandemic: Genomics Analysis of SARS-CoV-2 over Public GALAXY server. Preprints 2020, 2020050343 (doi: 10.20944/preprints202005.0343.v1).

Abstract

Citizen Science has come up to perform analytics over the SARS-CoV-2 genome. Public GALAXY servers provide an automated platform for genomics analysis. Study includes design of GALAXY workflows for RNASEQ assembly and annotation as well as genomic variant discovery and perform analysis across four samples of SARS-CoV-2 infected humans obtained from the local population of Wuhan, China. It provides information about transcriptomics and genomic variants across the SARS-CoV-2 genome. Study can be extended to perform evolutionary and comparative study across each species of coronaviruses. Augmented and integrated study with cheminformatics and immunoinformatics will be a way forward for drug discovery and vaccine development.

Supplementary and Associated Material

https://osf.io/8gq7k/: Submitted as a project over OSF.

Subject Areas

GALAXY; Assembly; Annotation; Genomic Variants Discovery; Workflow

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