Community Research Amid COVID-19 Pandemic: Genomics Analysis of SARS-CoV-2 over Public GALAXY server

Ambarish Kumar; Ali Haider Bangash; Bjoern Gruening

doi:10.20944/preprints202005.0343.v1

Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Version 1 : Received: 19 May 2020 / Approved: 21 May 2020 / Online: 21 May 2020 (09:57:42 CEST)

Citizen Science has come up to perform analytics over the SARS-CoV-2 genome. Public GALAXY servers provide an automated platform for genomics analysis. Study includes design of GALAXY workflows for RNASEQ assembly and annotation as well as genomic variant discovery and perform analysis across four samples of SARS-CoV-2 infected humans obtained from the local population of Wuhan, China. It provides information about transcriptomics and genomic variants across the SARS-CoV-2 genome. Study can be extended to perform evolutionary and comparative study across each species of coronaviruses. Augmented and integrated study with cheminformatics and immunoinformatics will be a way forward for drug discovery and vaccine development.

https://osf.io/8gq7k/: Submitted as a project over OSF.

GALAXY; Assembly; Annotation; Genomic Variants Discovery; Workflow

Biology and Life Sciences, Virology

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Community Research Amid COVID-19 Pandemic: Genomics Analysis of SARS-CoV-2 over Public GALAXY server

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