Working Paper Article Version 2 This version is not peer-reviewed

COVID-DenseNet: A Deep Learning Architecture to Detect COVID-19 from Chest Radiology Images

Version 1 : Received: 7 May 2020 / Approved: 9 May 2020 / Online: 9 May 2020 (04:54:34 CEST)
Version 2 : Received: 14 January 2021 / Approved: 15 January 2021 / Online: 15 January 2021 (12:59:20 CET)
Version 3 : Received: 12 February 2022 / Approved: 18 February 2022 / Online: 18 February 2022 (14:44:55 CET)

How to cite: Sarker, L.; Islam, M.M.; Hannan, T.; Ahmed, Z. COVID-DenseNet: A Deep Learning Architecture to Detect COVID-19 from Chest Radiology Images. Preprints 2020, 2020050151 Sarker, L.; Islam, M.M.; Hannan, T.; Ahmed, Z. COVID-DenseNet: A Deep Learning Architecture to Detect COVID-19 from Chest Radiology Images. Preprints 2020, 2020050151

Abstract

Coronavirus disease (COVID-19) is a pandemic infectious disease that has a severe risk of spreading rapidly. The quick identification and isolation of the affected persons is the very first step to fight against this virus. In this regard, chest radiology images have been proven to be an effective screening approach of COVID-19 affected patients. A number of AI based solutions have been developed to make the screening of radiological images faster and more accurate in detecting COVID-19. In this study, we are proposing a deep learning based approach using Densenet-121 to effectively detect COVID-19 patients. We incorporated transfer learning technique to leverage the information regarding radiology image learned by another model (CheXNet) which was trained on a huge Radiology dataset of 112,120 images. We trained and tested our model on COVIDx dataset containing 13,800 chest radiography images across 13,725 patients. To check the robustness of our model, we performed both two-class and three-class classifications and achieved 96.49% and 93.71% accuracy respectively. To further validate the consistency of our performance, we performed patient-wise k-fold cross-validation and achieved an average accuracy of 92.91% for three class task. Moreover, we performed an interpretability analysis using Grad-CAM to highlight the most important image regions in making a prediction. Besides ensuring trustworthiness, this explainability can also provide new insights about the critical factors regarding COVID-19. Finally, we developed a website that takes chest radiology images as input and generates probabilities of the presence of COVID-19 or pneumonia and a heatmap highlighting the probable infected regions. Code and models' weights are availabe.

Keywords

deep learning; CNN; DenseNet; COVID-19; transfer learning

Subject

Computer Science and Mathematics, Algebra and Number Theory

Comments (1)

Comment 1
Received: 15 January 2021
Commenter: Md. Mohaiminul Islam
Commenter's Conflict of Interests: Author
Comment: 1. Changed the introduction part, added more description.
2. Added more related works.
3. Revised the whole methodology section. Added more descriptions and details.
4. Added more experiments in the 'Results and Discussion' section.
5. Revised limitations and future works and conclusions.
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