Preprint
Review
Diagnosis and Treatment of Bone Metastases in Breast Cancer: Radiotherapy, Local Approach, and Systemic Therapy in a Guide for Clinicians
Submitted:
14 August 2020
Posted:
20 August 2020
You are already at the latest version
A peer-reviewed article of this preprint also exists.
Abstract
The standard care for metastatic breast cancer (MBC) is systemic therapies with imbrication of focal treatment for symptoms. Recently, thanks to implementation of radiological and metabolic exams and development of new target therapies, oligometastatic and oligoprogressive settings are even more common, paving the way to a paradigm change of focal treatments role. In fact, according to immunophenotype, radiotherapy can be considered with radical intent in these settings of patients. The aim of this literature review is to analyse available clinical data on prognosis of bone metastases from breast cancer and benefits of available treatments for developing a practical guide for clinicians.
Keywords:
bone metastasis
; breast cancer
; radiotherapy
; diagnostic imaging
; systemic therapies
Copyright: This open access article is published under a Creative Commons CC BY 4.0 license, which permit the free download, distribution, and reuse, provided that the author and preprint are cited in any reuse.
Downloads
499
Views
311
Comments
1
Subscription
Notify me about updates to this article or when a peer-reviewed version is published.
MDPI Initiatives
Important Links
© 2025 MDPI (Basel, Switzerland) unless otherwise stated