Clinical, Molecular and Epidemiological Characterization of the SARS-CoV2 Virus and the Coronavirus Disease 2019 (COVID-19): A Comprehensive Literature Review

Esteban Ortiz-Prado; Katherine Simbaña-Rivera; Lenin Gomez-Barreno; Mario Rubio-Neira; Linda P. Guaman; Nikolaos Kyriakidis; Claire Muslin; Ana Maria Gomez-Jaramillo; Carlos Barba; Domenica Cevallos; Hugo Sanchez-San Miguel; Luis Unigarro; Rasa Zalakeviciute; Naomi Gadian; Andrés López-Cortés

doi:10.20944/preprints202004.0283.v1

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preprints.org > medicine and pharmacology > epidemiology and infectious diseases > doi: 10.20944/preprints202004.0283.v1

Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Clinical, Molecular and Epidemiological Characterization of the SARS-CoV2 Virus and the Coronavirus Disease 2019 (COVID-19): A Comprehensive Literature Review

Esteban Ortiz-Prado

^* ,

Katherine Simbaña-Rivera

Ana Maria Gomez-Jaramillo

Carlos Barba

Domenica Cevallos

Hugo Sanchez-San Miguel

Version 1 : Received: 14 April 2020 / Approved: 16 April 2020 / Online: 16 April 2020 (15:55:12 CEST)

A peer-reviewed article of this Preprint also exists.

Ortiz-Prado, Esteban, Katherine Simbaña-Rivera, Lenin Gómez-Barreno, Mario Rubio-Neira, Linda P. Guaman, Nikolaos C. Kyriakidis, Claire Muslin, Ana María Gómez Jaramillo, Carlos Barba-Ostria, and Doménica Cevallos-Robalino. 2020. “Clinical, Molecular and Epidemiological Characterization of the SARS-CoV2 Virus and the Coronavirus Disease 2019 (COVID-19), a Comprehensive Literature Review.” Diagnostic Microbiology and Infectious Disease 115094. Ortiz-Prado, Esteban, Katherine Simbaña-Rivera, Lenin Gómez-Barreno, Mario Rubio-Neira, Linda P. Guaman, Nikolaos C. Kyriakidis, Claire Muslin, Ana María Gómez Jaramillo, Carlos Barba-Ostria, and Doménica Cevallos-Robalino. 2020. “Clinical, Molecular and Epidemiological Characterization of the SARS-CoV2 Virus and the Coronavirus Disease 2019 (COVID-19), a Comprehensive Literature Review.” Diagnostic Microbiology and Infectious Disease 115094.

Abstract

Coronaviruses are an extensive family of viruses that can cause disease in both animals and humans. The current classification of coronaviruses recognizes 39 species in 27 subgenera that belong to the family Coronaviridae. From those, at least seven coronaviruses are known to cause respiratory infections in humans. Four of these viruses can cause common cold-like symptoms, while others that infect animals can evolve and become infectious to humans. Three recent examples of this viral jumps include SARS CoV, MERS-CoV and SARS CoV-2 virus. They are responsible for causing severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS) and the most recently discovered coronavirus disease during 2019 (COVID-19).COVID-19, a respiratory disease caused by the SARS-CoV-2 virus, was declared a pandemic by the World Health Organization (WHO) on 11 March 2020. The rapid spread of the disease has taken the scientific and medical community by surprise. Latest figures from 14 April 2020 show more than 2 million people had been infected with the virus, causing more than 120,000 deaths in over 210 countries worldwide. The large amount of information we receive every day concerning this new disease is so abundant and dynamic that medical staff, health authorities, academics and the media are not able to keep up with this new pandemic. In order to offer a clear insight of the extensive literature available, we have conducted a comprehensive literature review of the SARS CoV-2 Virus and the Coronavirus Diseases 2019 (COVID-19).

Keywords

Covid-19; coronavirus; SARS-CoV-2; review; pandemic

Subject

Medicine and Pharmacology, Epidemiology and Infectious Diseases

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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