Preprint Communication Version 1 This version is not peer-reviewed

An Alternative to Ventilators to Support Critical COVID-19 Patients

Version 1 : Received: 9 April 2020 / Approved: 13 April 2020 / Online: 13 April 2020 (10:53:28 CEST)

How to cite: Pan, G.; Lyu, T.; Hunt, J. An Alternative to Ventilators to Support Critical COVID-19 Patients . Preprints 2020, 2020040210 (doi: 10.20944/preprints202004.0210.v1). Pan, G.; Lyu, T.; Hunt, J. An Alternative to Ventilators to Support Critical COVID-19 Patients . Preprints 2020, 2020040210 (doi: 10.20944/preprints202004.0210.v1).

Abstract

Critically ill patients with COVID-19 may develop serious respiratory difficulties, causing a significant reduction in blood oxygen saturation pressure. Physical Ventilation of the lungs is one of the main methods to help critically ill patients through the acute phase of infection. During extreme situations when dysfunctional lungs are filled with sticky sputum in the alveolus or when there are simply not enough ventilators to match the need, the mortality rate can be dramatically increased. Here, we propose an intravenous injection method that may increase and maintain the blood oxygen pressure at normal levels. The intravenous (IV) infusion contains oxygen nanobubbles in physiological saline solution (ONPS), in which the dissolved oxygen content can be 2-6 times higher than the normal oxygen solubility in pure water. This makes it possible to oxygenate blood with a small limited volume of IV fluid without the risk of gaseous bubble formation in blood vessels.

Subject Areas

COVID-19; oxygen nanobubble; intravenous therapy; ventilator

Comments (2)

Comment 1
Received: 14 April 2020
Commenter: Antonio Romanelli
The commenter has declared there is no conflict of interests.
Comment: Dear author I read with very interest this paper. Did you test this alternative system for oxygenation in animal model?
+ Respond to this comment
Response 1 to Comment 1
Received: 15 April 2020
Commenter: Gang Pan
The commenter has declared there is no conflict of interests.
Comment: Not yet. The animal test is currently in preparation by collabrating with medical research labs in China. We will appreciate if you have any professional suggestions.

We encourage comments and feedback from a broad range of readers. See criteria for comments and our diversity statement.

Leave a public comment
Send a private comment to the author(s)
Views 0
Downloads 0
Comments 2
Metrics 0


×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.