Submitted:
09 April 2020
Posted:
13 April 2020
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Preprints on COVID-19 and SARS-CoV-2
Abstract
The symptoms most commonly reported by patients affected by coronavirus disease 2019 (COVID-19) include cough, fever, and shortness of breath. However, other major events usually observed in COVID-19 patients (e.g. high blood pressure, thrombosis, pulmonary embolism) seem to suggest that the virus is targeting the endothelium, one of the largest organs in the human body. Herein, we report both clinical and preclinical evidence supporting the hypothesis that the endothelium is a key target organ of COVID-19.
Keywords:
Covid-19
; coronavirus
; cardiovascular disease
; thrombosis
; hypertension
; endothelial dysfunction
Copyright: This open access article is published under a Creative Commons CC BY 4.0 license, which permit the free download, distribution, and reuse, provided that the author and preprint are cited in any reuse.