Version 1
: Received: 9 April 2020 / Approved: 13 April 2020 / Online: 13 April 2020 (02:23:33 CEST)
How to cite:
Sardu, C.; Gambardella, J.; Morelli, M.B.; Wang, X.; Marfella, R.; Santulli, G. Is COVID-19 an Endothelial Disease? Clinical and Basic Evidence. Preprints2020, 2020040204 (doi: 10.20944/preprints202004.0204.v1).
Sardu, C.; Gambardella, J.; Morelli, M.B.; Wang, X.; Marfella, R.; Santulli, G. Is COVID-19 an Endothelial Disease? Clinical and Basic Evidence. Preprints 2020, 2020040204 (doi: 10.20944/preprints202004.0204.v1).
Cite as:
Sardu, C.; Gambardella, J.; Morelli, M.B.; Wang, X.; Marfella, R.; Santulli, G. Is COVID-19 an Endothelial Disease? Clinical and Basic Evidence. Preprints2020, 2020040204 (doi: 10.20944/preprints202004.0204.v1).
Sardu, C.; Gambardella, J.; Morelli, M.B.; Wang, X.; Marfella, R.; Santulli, G. Is COVID-19 an Endothelial Disease? Clinical and Basic Evidence. Preprints 2020, 2020040204 (doi: 10.20944/preprints202004.0204.v1).
Abstract
The symptoms most commonly reported by patients affected by coronavirus disease 2019 (COVID-19) include cough, fever, and shortness of breath. However, other major events usually observed in COVID-19 patients (e.g. high blood pressure, thrombosis, pulmonary embolism) seem to suggest that the virus is targeting the endothelium, one of the largest organs in the human body. Herein, we report both clinical and preclinical evidence supporting the hypothesis that the endothelium is a key target organ of COVID-19.
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Commenter: Fabio Strelo
The commenter has declared there is no conflict of interests.
Please, check the results from Swiss study :
http://www.en.usz.ch/media/press-releases/pages/covid-19-endotheliitis.aspx
The commenter has declared there is no conflict of interests.