Version 1
: Received: 12 March 2020 / Approved: 13 March 2020 / Online: 13 March 2020 (10:11:43 CET)
How to cite:
Telyshev, D.; Pugovkin, A.; Ephimov, I.; Markov, A.; Leonhardt, S.; Walter, M.; Karimov, J.; Selishchev, S. Evaluation of Left Ventricular Assist Device Electrical Current as a Predictor of Left Ventricular Recovery. Preprints2020, 2020030229. https://doi.org/10.20944/preprints202003.0229.v1
Telyshev, D.; Pugovkin, A.; Ephimov, I.; Markov, A.; Leonhardt, S.; Walter, M.; Karimov, J.; Selishchev, S. Evaluation of Left Ventricular Assist Device Electrical Current as a Predictor of Left Ventricular Recovery. Preprints 2020, 2020030229. https://doi.org/10.20944/preprints202003.0229.v1
Telyshev, D.; Pugovkin, A.; Ephimov, I.; Markov, A.; Leonhardt, S.; Walter, M.; Karimov, J.; Selishchev, S. Evaluation of Left Ventricular Assist Device Electrical Current as a Predictor of Left Ventricular Recovery. Preprints2020, 2020030229. https://doi.org/10.20944/preprints202003.0229.v1
APA Style
Telyshev, D., Pugovkin, A., Ephimov, I., Markov, A., Leonhardt, S., Walter, M., Karimov, J., & Selishchev, S. (2020). Evaluation of Left Ventricular Assist Device Electrical Current as a Predictor of Left Ventricular Recovery. Preprints. https://doi.org/10.20944/preprints202003.0229.v1
Chicago/Turabian Style
Telyshev, D., Jamshid Karimov and Sergey Selishchev. 2020 "Evaluation of Left Ventricular Assist Device Electrical Current as a Predictor of Left Ventricular Recovery" Preprints. https://doi.org/10.20944/preprints202003.0229.v1
Abstract
In this paper, we aim to assess the electric current parameters and report the analysis of the associated degree of ventricular recovery during left ventricular assist device (LVAD) support. An assumption was made there is a linear relationship between ventricular recovery degree and the pump electric current pulsatility index (PI). The experimental study was carried out using the ViVitro Pulse Duplicator System with Sputnik 1 LVAD connected. Cardiac output (CO) and cardiac power output (CPO) were used as a measure of ventricular recovery degree. Different heart rates (HR) (59, 73, 86 bpm) and pump speeds (7600–8400 rpm in 200 rpm steps) were investigated. Ventricular stroke volumes in the range of 30–80 ml for each heart rate at certain pump speed were used. The obtained relationships of CO and CPO vs. PI was linear as the coefficients of determination for each regression curve were more than 0.8. CO vs. PI: R2=0.9218; 0.9271; 0.9172 and CPO vs. PI: R2=0.8517; 0.841; 0.8244 for HR=59 bpm; 73 bpm; 86 bpm, respectively. Study findings suggest that adequate interpretation of parameters could potentially serve as a valuable clinical tool to assess ventricular recovery based on LVAD infrastructure without requiring any special hemodynamic assessment.
Keywords
heart failure; left ventricular assist device; cardiac recovery; mechanical circulation
Subject
Medicine and Pharmacology, Cardiac and Cardiovascular Systems
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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