Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Autodissemination of Pyriproxyfen as Novel Strategy to Control Dengue Outbreaks: A Review

Version 1 : Received: 11 March 2020 / Approved: 12 March 2020 / Online: 12 March 2020 (09:06:48 CET)

A peer-reviewed article of this Preprint also exists.

Journal reference: PERTANIKA JOURNAL OF SCIENCE & TECHNOLOGY 2020, 28, 1117-1140
DOI: 10.47836/pjst.28.4.01


The new emergence and re-emergence of arbovirus infections vectored by Aedes mosquitoes have been spread across Southeast Asia, Central Africa, United States, tropical Oceania and become a major of public health concerns. These arbovirus diseases found to have a similar vector, symptoms of the diseases and environments. The situation has become complicated without any specific vaccine or treatment for the diseases. As far as we concern, vector control is the best defense with many challenges, a scattered breeding site and biological behavioral sometimes, more difficult to control. Herein, we present a review of studies on current techniques proposed to combat arbovirus infections vectored by Aedes mosquitoes. A crucial gap in a vector control program is the inability to eliminate and destroy the cryptic breeding site by using conventional control methods. The idea and proper concept of using mosquitoes to bring insecticide to their oviposition site had been getting more interest in people to explore. Autodissemination is a self-delivery technique by manipulating the behavior of mosquitoes, carrying the insecticide and disseminate to cryptic breeding sites. This technique has shown a promising result in some countries and can be considered as additional tools in a vector control program


Aedes spp.; dengue; vector control; autodissemination; pyriproxyfen

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