Preprint Article Version 2 Preserved in Portico This version is not peer-reviewed

Exceptional Antioxidant, Non-Cytotoxic Activity of Integral Lemon Pectin from Hydrodynamic Cavitation

Domenico Nuzzo
ORCID logo ,
Laura Cristaldi
,
Marzia Sciortino
,
Lorenzo Albanese
,
Antonino Scurria
,
Federica Zabini
,
Claudia Lino
,
Mario Pagliaro
* ORCID logo ,
Francesco Meneguzzo
ORCID logo ,
Marta Di Carlo
,
Rosaria Ciriminna
ORCID logo
Version 1 : Received: 15 January 2020 / Approved: 16 January 2020 / Online: 16 January 2020 (03:14:23 CET)
Version 2 : Received: 17 March 2020 / Approved: 18 March 2020 / Online: 18 March 2020 (02:37:32 CET)
Version 3 : Received: 30 March 2020 / Approved: 31 March 2020 / Online: 31 March 2020 (05:00:13 CEST)

A peer-reviewed article of this Preprint also exists.

Nuzzo, D.; Cristaldi, L.; Sciortino, M.; Albanese, L.; Scurria, A.; Zabini, F.; Lino, C.; Pagliaro, M.; Meneguzzo, F.; Di Carlo, M.; et al. Exceptional Antioxidant, Non‐Cytotoxic Activity of Integral Lemon Pectin from Hydrodynamic Cavitation. ChemistrySelect 2020, 5, 5066–5071, doi:10.1002/slct.202000375. Nuzzo, D.; Cristaldi, L.; Sciortino, M.; Albanese, L.; Scurria, A.; Zabini, F.; Lino, C.; Pagliaro, M.; Meneguzzo, F.; Di Carlo, M.; et al. Exceptional Antioxidant, Non‐Cytotoxic Activity of Integral Lemon Pectin from Hydrodynamic Cavitation. ChemistrySelect 2020, 5, 5066–5071, doi:10.1002/slct.202000375.

Abstract

Lemon pectin extracted along with water-soluble flavonoids and other phytochemicals from citrus industry’s waste lemon peel via hydrodynamic cavitation in water, directly at pre-industrial scale and further isolated via freeze drying, shows exceptionally high antioxidant and non-cytotoxic activity. Preliminary investigation indicates also significant antimicrobial activity. These findings open the route to the development of new nutraceutical and healthcare application of a versatile biopolymer endowed with new functionality, rapidly and conveniently obtained from an abundant by-product of the agrofood industry.

Keywords

pectin; antioxidant; lemon; flavonoids; hydrodynamic cavitation; IntegroPectin

Subject

Biology and Life Sciences, Biochemistry and Molecular Biology

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Comments (1)

Comment 1
Received: 18 March 2020
Commenter: Mario Pagliaro
Commenter's Conflict of Interests: Author
Comment: Manuscript revised upon peer review at a major general chemistry journal published in Europe. The new manuscript is organized in sections and includes relevant new discussion on the antioxidant activity of IntegroPectin as well as comparison between hydrodynamic cavitation and microwave hydrodistillation, hydrodiffusion and gravity extraction methods applied to waste citrus peel.
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