Preprint Review Version 1 This version is not peer-reviewed

Graphene-Based Biosensors for Detection of Biomarkers

Version 1 : Received: 3 December 2019 / Approved: 4 December 2019 / Online: 4 December 2019 (03:00:03 CET)

How to cite: Bai, Y.; Xu, T.; Zhang, X. Graphene-Based Biosensors for Detection of Biomarkers. Preprints 2019, 2019120034 (doi: 10.20944/preprints201912.0034.v1). Bai, Y.; Xu, T.; Zhang, X. Graphene-Based Biosensors for Detection of Biomarkers. Preprints 2019, 2019120034 (doi: 10.20944/preprints201912.0034.v1).

Abstract

The development of biosensors with high sensitivity and low-detection limits provides a new direction for medical and personal care. Graphene and graphene derivatives have been used to prepare various types of biosensors due to their excellent sensing performance (e.g. high specific surface area, extraordinary electronic properties, electron transport capabilities and ultrahigh flexibility). This perspective review focuses on graphene-based biosensors for quantitative detection of cancer related biomarkers such as DNA, miRNA, small molecules and proteins by integrating with different signal outputting approaches including fluorescent, electrochemistry, surface plasmon resonance, surface enhanced Raman scattering etc. The article also discussed their challenges and potential solutions along with future prospects.

Subject Areas

graphene; graphene derivative; biosensor; detection; biomarker

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