Pavliuk, G.; Pavlov, D.; Mitsai, E.; Vitrik, O.; Mironenko, A.; Zakharenko, A.; Kulinich, S.A.; Juodkazis, S.; Bratskaya, S.; Zhizhchenko, A.; Kuchmizhak, A. Ultrasensitive SERS-Based Plasmonic Sensor with Analyte Enrichment System Produced by Direct Laser Writing. Nanomaterials2020, 10, 49.
Pavliuk, G.; Pavlov, D.; Mitsai, E.; Vitrik, O.; Mironenko, A.; Zakharenko, A.; Kulinich, S.A.; Juodkazis, S.; Bratskaya, S.; Zhizhchenko, A.; Kuchmizhak, A. Ultrasensitive SERS-Based Plasmonic Sensor with Analyte Enrichment System Produced by Direct Laser Writing. Nanomaterials 2020, 10, 49.
We report an easy-to-implement device for SERS-based detection of various analytes dissolved in water droplets at trace concentrations. The device combines an analyte-enrichment system and SERS-active sensor site, both produced via inexpensive and high-performance direct fs-laser printing. Fabricated on a surface of water-repellent polytetrafluoroethylene substrate as an arrangement of micropillars, the analyte-enrichment system supports evaporating water droplet in the Cassie-Baxter superhydrophobic state, thus ensuring delivery of the dissolved analyte molecules towards the hydrophilic SERS-active site. The efficient pre-concentration of the analyte onto the sensor site based on densely-arranged spiky plasmonic nanotextures results in its subsequent label-free identification by means of SERS spectroscopy. Using the proposed device, we demonstrate reliable SERS-based fingerprinting of various analytes, including common organic dyes and medical drugs at ppb concentrations. The proposed device is believed to find applications in various areas, including label-free environmental monitoring, medical diagnostics, and forensics.
direct laser processing; femtosecond laser pulses; superhydrophobic textures; analyte enrichment; plasmonic nanostructures; SERS; medical drugs
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