Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

ARSA-16S: A New and Conceptually Different Approach for 16S-based Taxonomic Profiling

Version 1 : Received: 12 September 2019 / Approved: 16 September 2019 / Online: 16 September 2019 (16:41:43 CEST)

How to cite: Pareja-Tobes, E.; Tobes, R. ARSA-16S: A New and Conceptually Different Approach for 16S-based Taxonomic Profiling. Preprints 2019, 2019090170. https://doi.org/10.20944/preprints201909.0170.v1 Pareja-Tobes, E.; Tobes, R. ARSA-16S: A New and Conceptually Different Approach for 16S-based Taxonomic Profiling. Preprints 2019, 2019090170. https://doi.org/10.20944/preprints201909.0170.v1

Abstract

Here we describe ARSA-16S, a tool and accompanying reference database for the analysis of bacterial 16S amplicons. Among other features, ARSA-16S is based on a new model, approach, and algorithm for sequence-level assignment of reads understood as probability distributions, assigns reads individually, and is designed with non-overlapping amplicons covering two non-contiguous regions. A new set of primers for the amplification and sequencing of the V4 and V6 regions is also provided.

Keywords

16S analysis, metagenomics, amplicons, bioinformatics, DNA sequencing

Subject

Biology and Life Sciences, Immunology and Microbiology

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.

Leave a public comment
Send a private comment to the author(s)
* All users must log in before leaving a comment
Views 0
Downloads 0
Comments 0
Metrics 0


×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.