This study investigated dry reforming of methane with combined catalysts supported on γ-Al2O3 support doped with 3.0 wt. % TiO2. The physicochemical properties of all the catalysts were determined by inductively-coupled plasma/mass spectrometry metal analysis, nitrogen physisorption, X-ray diffraction, temperature programmed reduction/desorption, thermogravimetric analysis, and scanning electron microscopy. The addition of CeO2 and MgO to Ni strengthened the interaction between the Ni and the support. The catalytic activity results indicated that the CeO2 and MgO addition to Ni did not do much in retarding carbon deposition, but they improved the activity of the catalysts. Among the tested catalysts, it was found that the catalyst with the composition of 5.0 wt % NiO-10.0 wt % CeO2/3.0 wt %TiO2-γ-Al2O3 resulted in the highest CH4 and CO2 conversion with H2/CO mole ratio close to unity. The optimum reaction conditions in terms of reactant conversion and H2/CO mole ratio were achieved by varying space velocity and CO2/CH4 mole ratio.