Preprint Article Version 1 This version is not peer-reviewed

Radiative Microwave Heating of Hyperthermia Therapy on Breast Cancer in a Porous Medium

Version 1 : Received: 14 October 2018 / Approved: 15 October 2018 / Online: 15 October 2018 (13:02:05 CEST)

How to cite: Oke, S.I.; Salawu, S.O.; Matadi, M.B.; Animasaun, I.L. Radiative Microwave Heating of Hyperthermia Therapy on Breast Cancer in a Porous Medium. Preprints 2018, 2018100313 (doi: 10.20944/preprints201810.0313.v1). Oke, S.I.; Salawu, S.O.; Matadi, M.B.; Animasaun, I.L. Radiative Microwave Heating of Hyperthermia Therapy on Breast Cancer in a Porous Medium. Preprints 2018, 2018100313 (doi: 10.20944/preprints201810.0313.v1).

Abstract

Cancer is a leading cause of morbidity and mortality worldwide, yet much is still unknown about its mechanism of establishment and destruction. Recently, studies had shown that tumor cells cannot survive under the high temperature conditions. This treatment technique is called Hyperthermia. This report presents the case of radiative microwave heating of hyperthermia therapy on breast cancer in a porous medium. In this study, the steady state is solved analytically while unsteady state is solved using semi-implicit finite difference to get a more accurate prediction of blood temperature distributions within the breast tissues. A moderate temperature hyperthermia treatment is apply which results into cell death due to an increase in the level of cell sensitivity to radiation therapy and blood flow in tumor and oxygen. The results show that by applying metabolic heat generation rate of $3.97 X 10^{5}Wm^{-3}$, it takes upto 2 minutes for the tumor cells to get the require therapeutic temperature point.

Subject Areas

hyperthermia treatment; bioheat transfer; breast cancer; radiation; biological tissue

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