Version 1
: Received: 9 October 2018 / Approved: 9 October 2018 / Online: 9 October 2018 (15:39:16 CEST)
How to cite:
Paredes, J.M.; Miguel, D.; Resa, S.; Gonzalez-Garcia, M.D.C.; Diaz-Torres, Y.; Cuerva, J.M.; Crovetto, L. Design, Synthesis and Photophysical Studies of Improved Xanthene Dye to Detect Acetate. Preprints2018, 2018100190 (doi: 10.20944/preprints201810.0190.v1).
Paredes, J.M.; Miguel, D.; Resa, S.; Gonzalez-Garcia, M.D.C.; Diaz-Torres, Y.; Cuerva, J.M.; Crovetto, L. Design, Synthesis and Photophysical Studies of Improved Xanthene Dye to Detect Acetate. Preprints 2018, 2018100190 (doi: 10.20944/preprints201810.0190.v1).
Cite as:
Paredes, J.M.; Miguel, D.; Resa, S.; Gonzalez-Garcia, M.D.C.; Diaz-Torres, Y.; Cuerva, J.M.; Crovetto, L. Design, Synthesis and Photophysical Studies of Improved Xanthene Dye to Detect Acetate. Preprints2018, 2018100190 (doi: 10.20944/preprints201810.0190.v1).
Paredes, J.M.; Miguel, D.; Resa, S.; Gonzalez-Garcia, M.D.C.; Diaz-Torres, Y.; Cuerva, J.M.; Crovetto, L. Design, Synthesis and Photophysical Studies of Improved Xanthene Dye to Detect Acetate. Preprints 2018, 2018100190 (doi: 10.20944/preprints201810.0190.v1).
Abstract
Development of biomarkers of analytes with interest in clinic is an important field of study. In this work, we synthesized and analyzed the new fluorescent acetate-biomarker, Iso-PG. The mechanism of detection is the acetate buffer mediated proton transfer reaction. The rate constants involved were obtained, and we measured the change in the fluorescence lifetime produced as a consequence of the presence of acetate in the medium. Finally, we checked its potential use as acetate biomarker in synthetic serum
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.