Paredes, J.M.; Miguel, D.; Resa, S.; Gonzalez-Garcia, M.D.C.; Diaz-Torres, Y.; Cuerva, J.M.; Crovetto, L. Design, Synthesis and Photophysical Studies of Improved Xanthene Dye to Detect Acetate. Preprints2018, 2018100190. https://doi.org/10.20944/preprints201810.0190.v1
APA Style
Paredes, J.M., Miguel, D., Resa, S., Gonzalez-Garcia, M.D.C., Diaz-Torres, Y., Cuerva, J.M., & Crovetto, L. (2018). Design, Synthesis and Photophysical Studies of Improved Xanthene Dye to Detect Acetate. Preprints. https://doi.org/10.20944/preprints201810.0190.v1
Chicago/Turabian Style
Paredes, J.M., Juan Manuel Cuerva and Luis Crovetto. 2018 "Design, Synthesis and Photophysical Studies of Improved Xanthene Dye to Detect Acetate" Preprints. https://doi.org/10.20944/preprints201810.0190.v1
Abstract
Development of biomarkers of analytes with interest in clinic is an important field of study. In this work, we synthesized and analyzed the new fluorescent acetate-biomarker, Iso-PG. The mechanism of detection is the acetate buffer mediated proton transfer reaction. The rate constants involved were obtained, and we measured the change in the fluorescence lifetime produced as a consequence of the presence of acetate in the medium. Finally, we checked its potential use as acetate biomarker in synthetic serum
Chemistry and Materials Science, Physical Chemistry
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
