Preprint Review Version 1 This version is not peer-reviewed

Oral Biofilms: Development, Control and Analysis

Version 1 : Received: 8 August 2018 / Approved: 9 August 2018 / Online: 9 August 2018 (00:20:24 CEST)

How to cite: Berger, D.; Rakamimova, A.; Pollack, A.; Loewy, Z. Oral Biofilms: Development, Control and Analysis. Preprints 2018, 2018080174 (doi: 10.20944/preprints201808.0174.v1). Berger, D.; Rakamimova, A.; Pollack, A.; Loewy, Z. Oral Biofilms: Development, Control and Analysis. Preprints 2018, 2018080174 (doi: 10.20944/preprints201808.0174.v1).

Abstract

The oral cavity harbors hundreds of microbial species that are present either as planktonic cells, or incorporated into biofilms. The majority of the oral microbes are commensal organisms. Those that are pathogenic microbes can result in oral infections, and at times initiate systemic diseases. Biofilms that contain pathogens have been challenging to control. Many conventional antimicrobials have proven to be ineffective. Recent advances in science and technology are providing new approaches for pathogen control and containment and methods to characterize biofilms. This perspective provides: 1) A general understanding of biofilm development; 2) A description of emerging chemical and biological methods to control oral biofilms; 3) An overview of high-throughput analytical approaches to analyze biofilms.

Subject Areas

biofilm; antimicrobial; high-throughput analysis

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