Preprint Article Version 1 This version is not peer-reviewed

Relating the Effect of HPA Axis to the Emotional State of Bipolar II Disorder Patient

Version 1 : Received: 22 July 2018 / Approved: 23 July 2018 / Online: 23 July 2018 (11:28:30 CEST)

How to cite: Michael, U.; Oyesanya, M. Relating the Effect of HPA Axis to the Emotional State of Bipolar II Disorder Patient. Preprints 2018, 2018070415 (doi: 10.20944/preprints201807.0415.v1). Michael, U.; Oyesanya, M. Relating the Effect of HPA Axis to the Emotional State of Bipolar II Disorder Patient. Preprints 2018, 2018070415 (doi: 10.20944/preprints201807.0415.v1).

Abstract

Using analytic approach we study the effect of HPA axis secretions to the emotional variation of bipolar II disorder patient. Modified Duffing – Van der Pol oscillator was used to model the emotional variation, that was solved analytically using multiple scale perturbation to obtain an asymptotic solution. The solution was graphed to understand the effect of the variation of the cortisol to the oscillator. It was observed that the increase or decrease of the HPA hormone from the basal level in the body system, affects the mood variation of bipolar II disorder patients.

Subject Areas

HPA axis, Bipolar II disorder, perturbation, cortisol

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