Version 1
: Received: 13 July 2018 / Approved: 16 July 2018 / Online: 16 July 2018 (09:06:33 CEST)
How to cite:
Ali Syed, S.; Bari, A.; Mahmood, A.; Abuelreich, S.; C. Hosten, E.; Betz, R.; M. AlObaid, A.; AlGhadeer, A. Evaluation of N-arylhydrazone derivatives of orotic acid as stimulators of human mesenchymal stem cell (hMSCs) differentiation.. Preprints2018, 2018070264. https://doi.org/10.20944/preprints201807.0264.v1
Ali Syed, S.; Bari, A.; Mahmood, A.; Abuelreich, S.; C. Hosten, E.; Betz, R.; M. AlObaid, A.; AlGhadeer, A. Evaluation of N-arylhydrazone derivatives of orotic acid as stimulators of human mesenchymal stem cell (hMSCs) differentiation.. Preprints 2018, 2018070264. https://doi.org/10.20944/preprints201807.0264.v1
Ali Syed, S.; Bari, A.; Mahmood, A.; Abuelreich, S.; C. Hosten, E.; Betz, R.; M. AlObaid, A.; AlGhadeer, A. Evaluation of N-arylhydrazone derivatives of orotic acid as stimulators of human mesenchymal stem cell (hMSCs) differentiation.. Preprints2018, 2018070264. https://doi.org/10.20944/preprints201807.0264.v1
APA Style
Ali Syed, S., Bari, A., Mahmood, A., Abuelreich, S., C. Hosten, E., Betz, R., M. AlObaid, A., & AlGhadeer, A. (2018). Evaluation of N-arylhydrazone derivatives of orotic acid as stimulators of human mesenchymal stem cell (hMSCs) differentiation.. Preprints. https://doi.org/10.20944/preprints201807.0264.v1
Chicago/Turabian Style
Ali Syed, S., Abdulrahman M. AlObaid and Abdulrahman AlGhadeer. 2018 "Evaluation of N-arylhydrazone derivatives of orotic acid as stimulators of human mesenchymal stem cell (hMSCs) differentiation." Preprints. https://doi.org/10.20944/preprints201807.0264.v1
Abstract
Human mesenchymal stem cells (hMSCs) constitute of cells having potential of self-renewal and proliferation and are commonly isolated from bone marrow aspirates of large bones. The osteogenic potential of these stem cells has been extensively exploited by scientists during the last many years for the biological evaluation of synthetic scaffolds with applications in tissue engineering. Current work aimed to synthesize N-arylhydrazone derivatives of orotic acid and their evaluation as stimulators of human mesenchymal stem cells. Some of the analogs show good to moderate proliferation rate.
Chemistry and Materials Science, Medicinal Chemistry
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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