Version 1
: Received: 23 April 2018 / Approved: 25 April 2018 / Online: 25 April 2018 (06:00:36 CEST)
Version 2
: Received: 19 June 2018 / Approved: 19 June 2018 / Online: 19 June 2018 (10:09:33 CEST)
Soares, MC, Gerlai, R, Maximino, C. The integration of sociality, monoamines and stress neuroendocrinology in fish models: applications in the neurosciences. J Fish Biol. 2018; 93: 170–191. https://doi.org/10.1111/jfb.13757
Soares, MC, Gerlai, R, Maximino, C. The integration of sociality, monoamines and stress neuroendocrinology in fish models: applications in the neurosciences. J Fish Biol. 2018; 93: 170–191. https://doi.org/10.1111/jfb.13757
Soares, MC, Gerlai, R, Maximino, C. The integration of sociality, monoamines and stress neuroendocrinology in fish models: applications in the neurosciences. J Fish Biol. 2018; 93: 170–191. https://doi.org/10.1111/jfb.13757
Soares, MC, Gerlai, R, Maximino, C. The integration of sociality, monoamines and stress neuroendocrinology in fish models: applications in the neurosciences. J Fish Biol. 2018; 93: 170–191. https://doi.org/10.1111/jfb.13757
Abstract
Animal-focused research has been crucial for scientific advancement however, in this matter, rodents are still taking a starring role. Coming out from merely being supportive of evidence found in rodents, the use of fish models has slowly taken a more central role and expanded its overall contributions in areas such as social sciences, evolution, physiology, and recently in translational medical research. In neurosciences, zebrafish has been widely adopted, contributing to our understanding of the genetic control of brain processes, and the effects of pharmacological manipulations. However, discussion continues regarding the paradox of function versus structure, when fish and mammals are compared, and on the potentially evolutionarily conserved nature of behaviour across fish species. From the behavioural stand point we explorted aversive/stress and social behaviour in selected fish models, and refer to the extensive contributions of stress and monoaminergic systems. We suggest that, in spite of marked neuroanatomical differences between fish and mammals, stress and sociality are conserved at the behavioural and molecular levels. We also suggest that stress and sociality are mediated by monoamines in predictable and non-trivial ways, and that monoamines could “bridge” the relationship between stress and social behaviour. To reconcile the level of divergence with the level of similarity, neuroanatomy, pharmacology, behavioural analysis, and ecology studies conducted in the laboratory and in nature need to add to each other and enhance our understanding of fish behaviour and ultimately how this all may translate to better model systems for translational studies.
Keywords
neuroendocrinology; social behaviour network; mesolimbic reward system; aversive behaviour network
Subject
Biology and Life Sciences, Anatomy and Physiology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
