Preprint Review Version 1 This version is not peer-reviewed

Acupuncture as Add-On Treatment of the Positive, Negative, and Cognitive Symptoms of Patients with Schizophrenia: A Systematic Review

Version 1 : Received: 22 February 2018 / Approved: 23 February 2018 / Online: 23 February 2018 (04:59:52 CET)

A peer-reviewed article of this Preprint also exists.

van den Noort, M.; Yeo, S.; Lim, S.; Lee, S.-H.; Staudte, H.; Bosch, P. Acupuncture as Add-On Treatment of the Positive, Negative, and Cognitive Symptoms of Patients with Schizophrenia: A Systematic Review. Medicines 2018, 5, 29. van den Noort, M.; Yeo, S.; Lim, S.; Lee, S.-H.; Staudte, H.; Bosch, P. Acupuncture as Add-On Treatment of the Positive, Negative, and Cognitive Symptoms of Patients with Schizophrenia: A Systematic Review. Medicines 2018, 5, 29.

Journal reference: Medicines 2018, 5, 29
DOI: 10.3390/medicines5020029

Abstract

Background: Schizophrenia is a severe psychiatric disorder that has a large impact on patients’ lives. In addition to Western medicine, the use of additional treatments, such as acupuncture, in treating the positive, negative, and cognitive symptoms is increasing. Methods: We conducted a systematic review on the use of acupuncture as an add-on treatment for patients with schizophrenia that are in regular care, with a special focus on the treatment of the often accompanying co-morbid sleep disorders. In this study, we searched the Medline, ScienceDirect, Cochrane Library, Scopus, and ERIC databases with a cut-off date of December 31, 2017, thereby following the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) protocol. Results: Our search resulted in 26 eligible studies. Most studies showed limited evidence for the use of acupuncture as add-on therapy in the treatment of clinical symptoms, but beneficial effects have been reported in the treatment of co-morbid sleep disorders. Conclusions: Limited evidence was found for the use of acupuncture as add-on therapy in the treatment of patients with schizophrenia; however, positive results were found in the treatment of sleep disorders, but this result needs to be confirmed in large, randomized, controlled trials.

Subject Areas

schizophrenia; psychosis; sleep; sleep disturbances; sleep disorders; integrative medicine; acupuncture; add-on therapy

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