Version 1
: Received: 26 December 2017 / Approved: 9 January 2018 / Online: 9 January 2018 (09:14:39 CET)
How to cite:
Hajj-Hassan, M.; Fayad, R.; Berro, S.; Chodavarapu, V.P.; Musallam, S. Implantation of Elongated Porous Silicon Neural Probe Array in Rat Cortex. Preprints2018, 2018010080. https://doi.org/10.20944/preprints201801.0080.v1
Hajj-Hassan, M.; Fayad, R.; Berro, S.; Chodavarapu, V.P.; Musallam, S. Implantation of Elongated Porous Silicon Neural Probe Array in Rat Cortex. Preprints 2018, 2018010080. https://doi.org/10.20944/preprints201801.0080.v1
Hajj-Hassan, M.; Fayad, R.; Berro, S.; Chodavarapu, V.P.; Musallam, S. Implantation of Elongated Porous Silicon Neural Probe Array in Rat Cortex. Preprints2018, 2018010080. https://doi.org/10.20944/preprints201801.0080.v1
APA Style
Hajj-Hassan, M., Fayad, R., Berro, S., Chodavarapu, V.P., & Musallam, S. (2018). Implantation of Elongated Porous Silicon Neural Probe Array in Rat Cortex. Preprints. https://doi.org/10.20944/preprints201801.0080.v1
Chicago/Turabian Style
Hajj-Hassan, M., Vamsy P. Chodavarapu and Sam Musallam. 2018 "Implantation of Elongated Porous Silicon Neural Probe Array in Rat Cortex" Preprints. https://doi.org/10.20944/preprints201801.0080.v1
Abstract
Neural microprobes represent an important component of neural prosthetic systems where implanted microprobes record the electro-potentials generated by specific thoughts in the brain and convey the signals to algorithms trained to interpret these thoughts. Here, we present novel elongated multi-site neural probe that can reach depths greater than 10mm. We hypothesize that reaching such depth allows the recording of cognitive signals required to drive cognitive prosthetics. The impedance of the recording sites on the probes was on the order of 500 kΩ at 1 kHz, which is consistent with probes used for neurophysiological recordings. The probes were made porous using Xenon Difluoride (XeF2) dry etching to improve the biocompatibility and their adherence to the surrounding neural tissue. Numerical studies were performed to determine the reliability of the porous probes. We implanted the elongated probe in rats and show that the elongated probes are capable of simultaneously recording both spikes and local field potentials (LFPs) from various recording sites.
Medicine and Pharmacology, Neuroscience and Neurology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
