Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

A Rapid Screening Test for the Diagnosis of Influenza Infection Incubation Period Using Coincidence Analysis of Pulse Waves

Version 1 : Received: 20 October 2017 / Approved: 20 October 2017 / Online: 20 October 2017 (09:54:02 CEST)

How to cite: Chen, P.; Tu, K.; Yu, S.; Yeh, W. A Rapid Screening Test for the Diagnosis of Influenza Infection Incubation Period Using Coincidence Analysis of Pulse Waves. Preprints 2017, 2017100137. https://doi.org/10.20944/preprints201710.0137.v1 Chen, P.; Tu, K.; Yu, S.; Yeh, W. A Rapid Screening Test for the Diagnosis of Influenza Infection Incubation Period Using Coincidence Analysis of Pulse Waves. Preprints 2017, 2017100137. https://doi.org/10.20944/preprints201710.0137.v1

Abstract

Viral infections have long been the biggest threat to human survival, and from a medical perspective, the development of noninvasive high-throughput screening methods that target the incubation period to either treat diseases or limit viral spread would be strikingly effective. Using this technology to target viral incubation periods would also be inexpensive to perform. The current study proposes to transform pulse signals into a rapid diagnostic test using “coincidence analysis” in the hope of preventing or reducing the symptoms of viral infections. The heart plays a critical role in calculating and supplying the needs of all tissues of the body. Pulse waves are pressurized signals in response to heart’s calculations and include all phases of the cardiac cycle, which maintains life and provides energy needed to perform tasks. Any small movement gives a corresponding signal to pulse waves. The current study investigated conclusive data on self-limiting infections, such as common cold. We used pulse wave, coincidence analysis technology to capture signals from individuals with common cold during the incubation period and investigated if particular characteristic signals could be applied to influenza during the incubation period. Preliminary work demonstrated that pulse waves could generate signals using this technology that would be worthwhile for future research. A small amount of analytical data from common cold existed previously. The data structure is based on the idea that a single pulse wave at differing physiological conditions would have slight modifications that would be amplified and presented by various geometrical shapes after extensive data are accumulated. These geometric shapes can then be sliced vertically or horizontally to extract data during different illness stages. The significance of these findings are impressive; from a personal or a public hygiene perspective, this analytical technology provides many benefits, such as rapid and precise decision-making that can be directly visualized or can be analyzed using software programs. Also, this technology also uses futuristic wearable technology that brings practical problem solving to physiology.

Keywords

influenza; pulse waves; incubation period; rapid diagnostic tests; coincidence analysis

Subject

Medicine and Pharmacology, Epidemiology and Infectious Diseases

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