Fostering Psychological Well-Being in Healthcare Professionals: A Dual-Level Intervention Model within the HPH&HS Framework

Background/Objectives: Healthcare professionals are exposed to chronic occupational stress and allostatic overload, with significant consequences for both workforce well-being and healthcare system sustainability. Within the framework of the Health Promoting Hospitals and Health Services (HPH&HS) network, the Friuli Centrale Healthcare University Trust (ASUFC) progressively developed a dual-level salutogenic approach aimed at promoting healthcare professionals’ resilience and psychophysiological well-being through integrated organizational and individual-oriented interventions. The present study describes the theoretical rationale, organizational implementation, and preliminary findings associated with this approach. Methods: The study adopted a practice-based and non-randomized implementation design conducted in a real-world healthcare setting. The model integrated two complementary interventions: the Mindfulness-Oriented Professional Resilience (MOPR) program, a structured group-based educational intervention, and the “Aver cura di chi ci cura” (“Caring for Those Who Care”) service, focused on individualized psychophysiological assessment, lifestyle counseling, and respiratory biofeedback. Results: Across the different implementation phases, the interventions were associated with preliminary improvements in psychological well-being, stress regulation, autonomic functioning, and resilience-related processes, while also supporting the progressive development of integrated organizational well-being pathways within the healthcare system. Conclusions: Preliminary findings suggest that integrated salutogenic interventions combining scalable group-based training with individualized multidimensional support may represent a feasible organizational strategy for promoting healthcare professionals’ well-being within large healthcare systems. Further controlled and longitudinal studies are needed to clarify long-term effectiveness, mechanisms of action, and organizational impact.