Submitted:
13 July 2026
Posted:
15 July 2026
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Abstract
Keywords:
1. Introduction
- We establish a formal definition for Heterogeneous Multi-Model Agents, where a central LLM coordinates probabilistic, specialized non-LLM models. We strictly distinguish HMMAs from deterministic tool-augmented LLMs, homogeneous multi-LLM systems, and unified multimodal LLMs by emphasizing their modularity and heterogeneous architectures.
- We review papers from major AI venues between 2023 and 2026, and identify 572 HMMA papers that meet our criteria. To organize the field, we categorize existing systems into five core interaction patterns based on their use of perception, generation, and action models. Building on this taxonomy, we map the literature across distinct application domains.
- We analyze HMMA design choices along five dimensions: information flow, interfaces, coupling, feedback, and uncertainty handling. We further discuss evaluation principles and summarize open challenges such as error cascading, interface bottlenecks, shallow alignment, and evaluation gaps.
2. Background
2.1. Definition
- Perception models extract structured information from raw sensory inputs. Examples include object detectors [106], segmentation models [83], depth estimators [96], OCR engines [46,143], and speech recognition models [66,134]. They turn pixels, waveforms, or screens into labels, boxes, masks, or text.
- Generation models synthesize new content in various modalities. Examples include image diffusion models [138], text-to-speech systems [43,82], video generators [32,182,202], and 3D asset creation models [81]. They turn a textual or structured plan into a concrete artifact such as an image, a clip of audio, or a 3D mesh.
2.2. Scope and Distinctions
2.2.0.1. Compound AI Systems.
2.2.0.2. Multi-agent Systems.
2.2.0.3. Multimodal LLMs (MLLMs).
2.2.0.4. Model Routing.
2.3. Survey Protocol
3. Taxonomy of Heterogeneous Multi-Model Agents
3.1. Overview
3.2. LLM with Perception

3.3. LLM with Perception and Action

3.4. LLM with Perception and Generation

3.5. LLM with Perception, Generation, and Action

3.6. LLM with Generation

4. Architectural Design and Analysis
4.1. LLM Roles in HMMA Orchestration
4.2. Frequently Used Specialized Models
4.3. Information Flow Topology
Iterative Closed-loop Topology.
Star-shaped Orchestration.
Sequential Pipelines.
DAG and Convergence Topologies.
4.4. Model Coupling
Loose Coupling.
Medium Coupling.
Tight Coupling.
Coupling by interaction pattern.
4.5. Feedback Structure
Iterative Refinement.
No Explicit Feedback.
Other Feedback Patterns.
4.6. Uncertainty Handling
No Uncertainty Handling.
LLM-based Verification.
Confidence Thresholding.
Retry and Fallback.
Other Uncertainty Mechanisms.
4.7. Inter-Model Interface Design
Discrete Symbolic Interfaces.
Continuous Representation Interfaces.

5. Application Domains
5.1. Visual Reasoning and Understanding
5.2. Embodied and GUI Agents
5.3. Multimodal Content Generation
5.4. Scientific and Medical Assistants
5.5. Additional Application Environments
Autonomous driving.
Video and audio generation.
Document understanding and retrieval-augmented systems.

6. Evaluation and Benchmarking
6.1. Evaluation Scope and Axes
6.2. Benchmark Settings and Metrics
6.3. Ablation and Counterfactual Evaluation
6.4. Failure Analysis, Human Evaluation, and Deployment
6.5. A Diagnostic Evaluation Protocol

7. Challenges and Future Directions
Error Cascading and System-level Uncertainty.
Interface Bottleneck.
Modularity vs. Alignment.
Coexistence with End-to-End Multimodal LLMs.
Benchmark Infrastructure.
HMMA as Model-Oriented Agent Harness.
8. Conclusions
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| Dimension | Category | Share (%) |
|---|---|---|
| Information flow | Iterative | 41.1 |
| Star | 29.0 | |
| Sequential | 21.0 | |
| DAG | 6.8 | |
| Convergence | 2.1 | |
| Model coupling | Loose | 62.2 |
| Medium | 36.0 | |
| Tight | 1.7 | |
| Feedback structure | Iterative refinement | 56.5 |
| None | 28.3 | |
| Cross-model feedback | 7.7 | |
| Self-correction | 4.7 | |
| Human-in-the-loop | 2.8 | |
| Uncertainty handling | None | 35.8 |
| LLM/VLM verification | 29.2 | |
| Confidence threshold | 15.4 | |
| Retry / fallback | 9.8 | |
| Cascaded filtering | 4.9 | |
| Voting / ensemble | 4.7 | |
| Interface design | Symbolic | 62.6 |
| Mixed | 35.5 | |
| Continuous | 1.9 |
| LLM role | Function in the HMMA | Count |
|---|---|---|
| Planner | Decompose a task into sub-goals | 566 |
| Coordinator | Schedule and dispatch specialist models | 515 |
| Reasoner | Combine intermediate outputs and infer | 560 |
| Reflector | Monitor and revise its own decisions | 302 |
| Verifier | Check whether a result satisfies the goal | 242 |
| Translator | Convert between modality-specific formats | 239 |
| Router | Select among interchangeable specialists | 222 |
| Perception | Generation | ||
|---|---|---|---|
| CLIP [133] | 100 | Stable Diffusion [138] | 45 |
| SAM [83] | 35 | ControlNet [197] | 16 |
| GroundingDINO [107] | 34 | SDXL [129] | 10 |
| BLIP-2 [90] | 32 | DALL-E 3 | 10 |
| GPT-4V | 14 | InstructPix2Pix [19] | 5 |
| GLIP [92] | 11 | Flux [84] | 6 |
| OWL-ViT [119] | 8 | VideoCrafter [32] | 4 |
| Whisper [134] | 8 | DALL-E | 4 |
| DINOv2 [125] | 8 | – | – |
| Action | |||
| Diffusion Policy [16] (5); CLIPort [142] (4); PPO policy (3). | |||
| Pattern | Loose | Medium | Tight | Total |
|---|---|---|---|---|
| P | 165 | 47 | 2 | 214 |
| P+A | 80 | 81 | 5 | 166 |
| P+G | 78 | 57 | 1 | 136 |
| G | 18 | 11 | 1 | 30 |
| P+G+A | 15 | 10 | 1 | 26 |
| Total | 356 | 206 | 10 | 572 |
| Dimension | Representative designs | Representative papers | Main architectural tension |
|---|---|---|---|
| Information flow | Sequential, star, iterative, DAG, convergence | VisProg [59]; Chameleon [112]; SayCan [6] | Static simplicity vs. adaptive closed-loop control |
| Interface design | Text, code, JSON, boxes, masks, embeddings, adapters | GroundingDINO [107]; SAM [83]; BLIP-2 [90] | Interpretability and replaceability vs. representational fidelity |
| Feedback structure | Iterative refinement, cross-model feedback, human feedback | Inner Monologue [73]; KnowNo [137] | Robust correction vs. latency and control complexity |
| Uncertainty handling | Thresholding, verification, fallback, ensemble | Woodpecker [189]; GroundingDINO [107] | Local confidence estimates vs. system-level uncertainty propagation |
| Model coupling | Loose, medium, tight | Socratic Models [193]; HuggingGPT [140]; RT-2 [18] | Modularity and low cost vs. cross-model alignment |
| Domain | Count | Pattern | Typical specialized models | Representative systems |
|---|---|---|---|---|
| Visual QA & reasoning | 127 | P | CLIP, GroundingDINO, SAM | ViperGPT [150], Chameleon [112] |
| Robot manipulation | 67 | P+A | SAM, Diffusion Policy, CLIPort | RoboGen [160], Video Lang. Planning [47] |
| Multi-domain & benchmarks | 63 | P (+G/A) | Mixed model pools | HuggingGPT [140], LLaVA-Plus [104] |
| Image gen. & editing | 60 | P+G | Stable Diffusion, ControlNet | GenArtist [161], Idea2Img [183] |
| Embodied navigation | 55 | P+A | Depth estimators, scene graphs | SG-Nav [187], TANGO [210] |
| GUI & web agents | 31 | P+A | UI grounding, OCR, DOM parsers | Agent S2 [4] |
| Medical analysis | 26 | P (±G/A) | Medical imaging CNNs, segmentation | Clinical reasoning agents [87] |
| 3D generation | 20 | P+G | Shape generators, renderers | LLM-guided 3D synthesis [45] |
| Scientific discovery | 20 | P (+G/A) | Protein and molecule predictors | Domain research agents [145] |
| Gaming | 19 | P+A | Vision encoders, RL and BC policies | ADAM [190], open-world agents [207] |
| Autonomous driving | 17 | P+A | Lane detectors, tracking models | Driving decision agents [61] |
| Benchmark evaluation | 13 | P (+A/G) | Evaluators, simulators | Agent evaluation frameworks [177] |
| Video generation | 12 | P+G | Video diffusion, captioners | LLM-guided video generation [179] |
| Audio and speech | 11 | P/G | ASR, TTS, audio generators | Audio generation agents [173] |
| Document understanding | 10 | P | OCR, layout parsers, table extractors | VisDoM [148], DocIA [115] |
| Retrieval-augmented | 10 | P | Multimodal retrievers, rankers | Ask [2], FineRAG [192], ViMoRAG [175] |
| Code development | 2 | P+A | Code models, edit verifiers | Coding agents |
| Other | 9 | Mixed | Task-specific specialists | Miscellaneous HMMA systems |
| Setting | Representative benchmarks or studies | Common signals | HMMA-specific additions needed |
|---|---|---|---|
| Visual and document reasoning | VQA, grounding, visual programming, dynamic VQA, and multimodal document QA [39,95,148,169] | Answer accuracy, localization, retrieval quality, evidence selection | Evidence provenance, missed-evidence analysis, and first-error attribution. |
| Embodied and GUI agents | Navigation, manipulation, screen control, web interaction, and cross-environment agents [3,5,94,177,187] | Success rate, task completion, path length, invalid actions | State drift, outdated observations, unsafe actions, and recovery after wrong steps. |
| Content generation | Image, video, diagram, editing, layout, and 3D generation [36,37,45,165,194] | Human preference, prompt alignment, artifact quality, edit success | Constraint satisfaction, repair quality, controllability, and verifier disagreement. |
| Medical, scientific, and safety-critical assistants | Clinical QA, tumor analysis, molecule or catalyst design, autonomous driving, and fact checking [17,48,93,116,145,201] | Domain accuracy, expert judgment, retrieved evidence quality, safety | Calibration, abstention, expert handoff, and the cost of wrong recommendations. |
| Agent and workflow frameworks | Tool execution, workflow generation, model routing, GUI control, and general computer control [55,109,126,151,180,208] | Tool-call correctness, completion rate, latency, cost | Specialist uncertainty, interface loss, and counterfactual module swaps. |
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