Background/Objectives: Pressure ulcers remain a significant clinical problem in palliative care. Identifying risk factors can support early intervention and prevention strategies. This study aimed to calculate the prevalence of pressure ulcers among palliative care patients, evaluate associated risk factors, enhance patients’ quality of life and care, and contribute significantly to the literature. Methods: This retrospective, descriptive, and correlational study was conducted between April 1, 2018, and November 30, 2023. Among 1,942 patients hospitalized in the Palliative Care Unit of Tokat Gaziosmanpaşa University Hospital, the medical records of 279 patients with pressure ulcers were retrospectively reviewed. The collected data included patients’ demographic characteristics, pressure ulcer risk factors, and Braden Pressure Ulcer Risk Assessment Scale scores. Results: The incidence of pressure ulcers was found to be 14.36%. Of the patients with pressure ulcers, 217 (77.8%) had pressure ulcers at the time of admission to the unit, while 62 (22.2%) developed pressure ulcers during hospitalization. The evaluated risk factors (age, use of medical devices and invasive procedures, type of nutrition, urinary and fecal elimination status, comorbidity status, mobility status, level of consciousness, and primary diagnosis) were found to be significantly associated with pressure ulcer development. Conclusion: In line with the data and results obtained, our hypothesis— “As a patient’s immobility increases, risk factors increase; consequently, the Braden Pressure Ulcer Risk Assessment Scale score decreases, and the likelihood of pressure ulcer development increases”—was supported. It is believed that this study will contribute to and guide researchers, healthcare professionals, and administrators interested in the field of palliative care.