Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Serum Antibody Titers against Distemper, Parvovirus and In-fectious Hepatitis in Dogs from Central Spain

Version 1 : Received: 15 May 2024 / Approved: 16 May 2024 / Online: 16 May 2024 (11:55:26 CEST)

How to cite: BLANCO, J. L.; PARRA, E.; RUBIES, S.; ORTIZ-DIEZ, G.; GARCIA, M. E. Serum Antibody Titers against Distemper, Parvovirus and In-fectious Hepatitis in Dogs from Central Spain. Preprints 2024, 2024051072. https://doi.org/10.20944/preprints202405.1072.v1 BLANCO, J. L.; PARRA, E.; RUBIES, S.; ORTIZ-DIEZ, G.; GARCIA, M. E. Serum Antibody Titers against Distemper, Parvovirus and In-fectious Hepatitis in Dogs from Central Spain. Preprints 2024, 2024051072. https://doi.org/10.20944/preprints202405.1072.v1

Abstract

A canine population’s immune resistance to canine distemper virus (CDV), canine parvovirus (CPV), and infectious hepatitis virus (CAV-1) was evaluated. In this study, a total of 112 sera were analyzed. Animals were considered as vaccinated if, in the last two years, they had re-ceived at least one dose of a vaccine that provides joint protection against CDV, CPV, and CAV-1. Animals that had never received any dose of these vaccines were designated as non-vaccinated. CDV, CPV, and CAV-1 antibodies were detected via a modified solid-phase enzyme-linked im-munosorbent assay (ELISA), which detects IgG antibody levels in sera and provides semi-quantitative results in less than 30 min. In total, 41.1% of the dogs had been vaccinated, and 58.9% of dogs were designated as non-vaccinated. Overall, 90.2%, 92.0%, and 78.6% of the tested dogs had positive results for the presence of IgG antibodies against CPV, CDV, and CAV-1, re-spectively. CPV antibodies were present in 93.5% (43/46) of the vaccinated and 87.9% (58/66) of the non-vaccinated dogs, while CDV antibodies were present in 95.5% (63/66) of the vaccinated and 87.0% (40/46) of the non-vaccinated dogs. Finally, CAV-1 antibodies were present in 84.8% (56/66) of the vaccinated and of 69.6% (32/46) the non-vaccinated dogs.

Keywords

Canine Distemper Virus; Canine Parvovirus; Infectious Hepatitis Virus; IgG level; Vaccicheck

Subject

Medicine and Pharmacology, Veterinary Medicine

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