Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Better Outcome of Females, Compared to Males with HIV-1 Infection

Shira Bezalel-Rosenberg
,
Keren Mahlab-Guri
,
Nadav Itai
,
Laliv Kadar
,
Shay Nemet
,
Ilan Asher
,
Ramon Cohen
,
Zev Moshe Sthoager
,
Hila Elinav
,
Daniel Elbirt
*
Version 1 : Received: 30 April 2024 / Approved: 30 April 2024 / Online: 1 May 2024 (16:47:38 CEST)

How to cite: Bezalel-Rosenberg, S.; Mahlab-Guri, K.; Itai, N.; Kadar, L.; Nemet, S.; Asher, I.; Cohen, R.; Sthoager, Z. M.; Elinav, H.; Elbirt, D. Better Outcome of Females, Compared to Males with HIV-1 Infection. Preprints 2024, 2024050014. https://doi.org/10.20944/preprints202405.0014.v1 Bezalel-Rosenberg, S.; Mahlab-Guri, K.; Itai, N.; Kadar, L.; Nemet, S.; Asher, I.; Cohen, R.; Sthoager, Z. M.; Elinav, H.; Elbirt, D. Better Outcome of Females, Compared to Males with HIV-1 Infection. Preprints 2024, 2024050014. https://doi.org/10.20944/preprints202405.0014.v1

Abstract

Introduction – Gender influences the presentation and progression of various diseases. Studies regarding the impact of gender on the course and outcome of HIV demonstrate conflicting data. Studies may be biased due to socioeconomic status differences between females and males and uneven gender representation, among other factors. In order to minimize the effect of non-biological elements this study cohort compares HIV males and females with similar ethnicity and social class in 2 Israeli AIDS centers. Methods –the study is a retrospective study. The cohort consists 334 females and 223 males diagnosed with HIV during the years 2000-2015. All patients were immigrants from Ethiopia who acquired HIV heterosexually and had a similar socioeconomic status. Data regarding demographics, clinical status, virological (viral load; VL), immunological (CD4) and treatment modalities were collected for each patient. Results - At the time of HIV diagnosis, males were older (43.2 ±13.2 vs. 35.4±11.95 years; p

Keywords

HIV; AIDS; Gender; Women; Outcome

Subject

Medicine and Pharmacology, Epidemiology and Infectious Diseases

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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