Preprint Case Report Version 1 Preserved in Portico This version is not peer-reviewed

A Rare Onset of T Lymphoid Blast Crisis in Chronic Myeloid Leukemia with Two Distinct Blast Populations

Version 1 : Received: 25 March 2024 / Approved: 26 March 2024 / Online: 27 March 2024 (06:21:04 CET)

How to cite: Mongia, A.; Romano, F.; Ciullini Mannurita, S.; Peruzzi, B.; Bencini, S.; Parrini, D.; Fasano, L.; Fanelli, A. A Rare Onset of T Lymphoid Blast Crisis in Chronic Myeloid Leukemia with Two Distinct Blast Populations. Preprints 2024, 2024031619. https://doi.org/10.20944/preprints202403.1619.v1 Mongia, A.; Romano, F.; Ciullini Mannurita, S.; Peruzzi, B.; Bencini, S.; Parrini, D.; Fasano, L.; Fanelli, A. A Rare Onset of T Lymphoid Blast Crisis in Chronic Myeloid Leukemia with Two Distinct Blast Populations. Preprints 2024, 2024031619. https://doi.org/10.20944/preprints202403.1619.v1

Abstract

In chronic myeloid leukemia (CML), a clonal proliferative disorder of granulocytic lineage, the 90%‐95% of cases are characterized by t(9;22) (q34.1;q11.2) translocation, leading to the Philadelphia chromosome (1). Rarely, CML patients directly present a blast crisis, mostly of myeloid origin (2, 3). Herein, we describe one rare CML case, showing an unusual early T lymphoid blastic crisis.

Keywords

chronic myeloid leukemia; T lymphoid blastic crisis

Subject

Medicine and Pharmacology, Hematology

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