Loriamini, M.; Cserti-Gazdewich, C.; Branch, D.R. Autoimmune Hemolytic Anemias: Classifications, Pathophysiology, Diagnoses and Management. Int. J. Mol. Sci.2024, 25, 4296.
Loriamini, M.; Cserti-Gazdewich, C.; Branch, D.R. Autoimmune Hemolytic Anemias: Classifications, Pathophysiology, Diagnoses and Management. Int. J. Mol. Sci. 2024, 25, 4296.
Loriamini, M.; Cserti-Gazdewich, C.; Branch, D.R. Autoimmune Hemolytic Anemias: Classifications, Pathophysiology, Diagnoses and Management. Int. J. Mol. Sci.2024, 25, 4296.
Loriamini, M.; Cserti-Gazdewich, C.; Branch, D.R. Autoimmune Hemolytic Anemias: Classifications, Pathophysiology, Diagnoses and Management. Int. J. Mol. Sci. 2024, 25, 4296.
Abstract
Autoimmune hemolytic anemias (AIHAs) are conditions whereby a person produces an antibody to their own red blood cells (RBCs). These conditions can be primary with unknown cause or secondary, associated with diseases or infections. There are seven different categories of AIHA, warm-antibody AIHA (wAIHA); cold-antibody AIHA that includes cold agglutinin syndrome (CAS) and cold agglutin disease (CAD); mixed AIHA, also called combined cold and warm AIHA; paroxysmal cold hemoglobinuria (PCH) also termed Donath-Lansteiner test-positive AIHA; direct antiglobulin test-negative AIHA (DAT-neg AIHA); drug-induced immune hemolytic anemia (DIIHA); and passenger lymphocyte syndrome. This review will discuss each of these AIHAs and provide information on diagnosis and treatment.
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