Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Innovative developments in Deep Brain Stimulation devices

Version 1 : Received: 14 February 2024 / Approved: 14 February 2024 / Online: 14 February 2024 (11:27:50 CET)

How to cite: Della Torre, A.; La Torre, D.; Guzzi, G.; Lo Turco, E.; Lavano, A. Innovative developments in Deep Brain Stimulation devices. Preprints 2024, 2024020800. https://doi.org/10.20944/preprints202402.0800.v1 Della Torre, A.; La Torre, D.; Guzzi, G.; Lo Turco, E.; Lavano, A. Innovative developments in Deep Brain Stimulation devices. Preprints 2024, 2024020800. https://doi.org/10.20944/preprints202402.0800.v1

Abstract

Technological advances in DBS hardware and software represent a significant growth area in functional neurosurgery. These advancements have the potential to significantly enhance treatment outcomes and expand the scope of neurological disorders that can be effectively addressed through DBS interventions. The introduction of directional DBS marks a new phase in neuromodulation, offering extended benefits for patients with Parkinson's disease, more efficient optimization of clinical outcomes, and targeted treatment of refractory symptoms through data-driven approaches. Implementing a multimodal programming strategy, incorporating novel current fractionation technology and image-guided tools for lead localization and brain sensing, further reduces reliance on traditional trial-and-error programming methods, paving the way for a more predictive application of this therapy. These advancements are expected to drive the development of sophisticated closed-loop stimulation systems capable of integrating continuous data streams for improved patient care.

Keywords

deep brain stimulation; directional leads; neuromodulation.

Subject

Medicine and Pharmacology, Neuroscience and Neurology

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