Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Postoperative Myocardial Infarction After Non-cardiac Surgery. An Update.

Version 1 : Received: 24 January 2024 / Approved: 24 January 2024 / Online: 24 January 2024 (14:24:42 CET)

A peer-reviewed article of this Preprint also exists.

Rostagno, C.; Craighero, A. Postoperative Myocardial Infarction after Non-Cardiac Surgery: An Update. J. Clin. Med. 2024, 13, 1473. Rostagno, C.; Craighero, A. Postoperative Myocardial Infarction after Non-Cardiac Surgery: An Update. J. Clin. Med. 2024, 13, 1473.

Abstract

Approximately 300 million non-cardiac surgeries are performed each year. Perioperative mortality after non-cardiac surgery is estimated at 2% in patients over 45 years of age . Half of these deaths are attributable to cardiovascular complications, and most to perioperative myocardial infarction (MINS). Before introduction of cardiac biomarkers the diagnosis of postoperative myocardial infarction was based on symptoms and electrocardiographic changes and its incidence was largely underestimated. The incidence of MINS when standard troponin assay is used ranges between 8 and 19% but increases to 20-30% whit high sensitivity troponin assays. Higher troponin values sugegsting myocardial injury , both with or without definite diagnosis of myocardial infarction, are associated with increased 30 day and 1-year mortality . Diagnostic and therapeutic strategies are reported .

Keywords

non-cardiac surgery, myocardial infarction/injury, troponin

Subject

Medicine and Pharmacology, Cardiac and Cardiovascular Systems

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