Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Epidemiological Profile of Bechcet’s Disease in Hospitalized Patients Infected With SARS-CoV-2 in Brazil: A Serial Case Report and a Literature Review

Version 1 : Received: 19 January 2024 / Approved: 19 January 2024 / Online: 19 January 2024 (08:00:20 CET)

How to cite: Valencise, F.E.; Filho, J.A.P.P.; Martins, J.P.; Marson, F.A.L. Epidemiological Profile of Bechcet’s Disease in Hospitalized Patients Infected With SARS-CoV-2 in Brazil: A Serial Case Report and a Literature Review. Preprints 2024, 2024011461. https://doi.org/10.20944/preprints202401.1461.v1 Valencise, F.E.; Filho, J.A.P.P.; Martins, J.P.; Marson, F.A.L. Epidemiological Profile of Bechcet’s Disease in Hospitalized Patients Infected With SARS-CoV-2 in Brazil: A Serial Case Report and a Literature Review. Preprints 2024, 2024011461. https://doi.org/10.20944/preprints202401.1461.v1

Abstract

The literature is scarce in the evaluation of Behçet’s disease (BD) among individuals during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Then, an epidemiological study was conducted using the data from 46 hospitalized patients with BD and coronavirus disease (COVID)-19 representing a prevalence of 2,11 patients per 100,000 inhabitants. From the study sample, 58.7% (27 patients) were female, and 67.4% (31 patients) were White. The main symptoms were fever (40; 87.0%), cough (38; 82.6%), dyspnea (35; 76.1%), and peripheral saturation below 95% (35%, 76.1%). The need for intensive care unit support occurred for 39.1% (18) patients. Also, 21.7% (10) patients needed invasive ventilatory support and 47.8% (22) needed non-invasive ventilatory support. A total of 73.9% (34) of patients lived, and 26.1% (12) of patients died. Only the presence of respiratory discomfort [37.9% vs. 5.9%] was more common among those who died. Patients with BD were not at an increased risk of worse COVID-19 outcomes in Brazil.

Keywords

Brazil; Coronavirus Disease (COVID)-19; Epidemiology; Inflammation; Pandemic; Public Health.

Subject

Medicine and Pharmacology, Epidemiology and Infectious Diseases

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