Version 1
: Received: 18 January 2024 / Approved: 18 January 2024 / Online: 18 January 2024 (14:48:36 CET)
How to cite:
Carminati, M.; Isel, F.; Houenou, J.; Wessa, M.; Henry, C. Impaired Regulation of Emotion in Bipolar Disorder: Behavioral and Neurophysiological Signatures. Preprints2024, 2024011429. https://doi.org/10.20944/preprints202401.1429.v1
Carminati, M.; Isel, F.; Houenou, J.; Wessa, M.; Henry, C. Impaired Regulation of Emotion in Bipolar Disorder: Behavioral and Neurophysiological Signatures. Preprints 2024, 2024011429. https://doi.org/10.20944/preprints202401.1429.v1
Carminati, M.; Isel, F.; Houenou, J.; Wessa, M.; Henry, C. Impaired Regulation of Emotion in Bipolar Disorder: Behavioral and Neurophysiological Signatures. Preprints2024, 2024011429. https://doi.org/10.20944/preprints202401.1429.v1
APA Style
Carminati, M., Isel, F., Houenou, J., Wessa, M., & Henry, C. (2024). Impaired Regulation of Emotion in Bipolar Disorder: Behavioral and Neurophysiological Signatures. Preprints. https://doi.org/10.20944/preprints202401.1429.v1
Chicago/Turabian Style
Carminati, M., Michèle Wessa and Chantal Henry. 2024 "Impaired Regulation of Emotion in Bipolar Disorder: Behavioral and Neurophysiological Signatures" Preprints. https://doi.org/10.20944/preprints202401.1429.v1
Abstract
Patients with bipolar disorder (BD) experience more frequent and intense emotions in response to environmental conditions relative to healthy subjects, which leads to mood instability. The aim of this study was to investigate the time-course of emotion regulation strategies, distraction, and reappraisal, in euthymic BD patients using electroencephalography (EEG). Fourteen BD patients and 13 matched healthy controls took part in an experiment constituted of three conditions, i.e., a passive viewing of positive, negative, and neutral pictures and two regulation conditions, one with reappraisal strategy and the other with distraction strategy. Critically, ERP results indicated that during passive viewing, the Late Positive Potential (LPP) was larger in BD patients compared with healthy controls, but only for neutral pictures. During emotion regulation, LPP amplitude was reduced in distraction condition compared with viewing one, especially for negative emotions in both patients and controls. Importantly, LPP was reduced in reappraisal condition compared with passive viewing in an early time window for negative emotions and in a later time window for positive emotions in controls but not in patients. Our findings showed that the neurochronometry of emotion regulation is faster for negative than for positive emotion in controls but not in BD patients.
Keywords
bipolar disorder; emotion regulation; EEG; late positive potential
Subject
Public Health and Healthcare, Other
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
