Preprint Brief Report Version 1 Preserved in Portico This version is not peer-reviewed

Restorative Reproductive Medicine: An Emerging New Treatment Process and a Prerequisite to Assisted Reproductive Technology for Treatment of Infertility.

Version 1 : Received: 5 January 2024 / Approved: 8 January 2024 / Online: 8 January 2024 (13:43:16 CET)

How to cite: Boyle, P.C.; Toth, A.; ONeill, L.; Turczynski, C.J. Restorative Reproductive Medicine: An Emerging New Treatment Process and a Prerequisite to Assisted Reproductive Technology for Treatment of Infertility.. Preprints 2024, 2024010624. https://doi.org/10.20944/preprints202401.0624.v1 Boyle, P.C.; Toth, A.; ONeill, L.; Turczynski, C.J. Restorative Reproductive Medicine: An Emerging New Treatment Process and a Prerequisite to Assisted Reproductive Technology for Treatment of Infertility.. Preprints 2024, 2024010624. https://doi.org/10.20944/preprints202401.0624.v1

Abstract

Abstract: The use of IVF and related procedures has offered opportunities for couples to conceive who otherwise would remain childless. This technology is often viewed as the only option but is very expensive and not highly effective. ln an effort to improve access to care, governments are attempting to provide funding. In Ireland for example the Health Service Executive (HSE) has recently made IVF funding available through Regional Fertility Hubs. for couples who qualify. However, this policy has threatened a less invasive approach available in Ireland that can help many couples before IVF is employed. We propose that a newly emerging “medical treatment process” called Restorative Reproductive Medicine (RRM), combined with methods or apps that track biomarkers of the menstrual cycle as a prerequisite option for appropriate patients. To illustrate the effectiveness, we compared live birth rates from an established Irish RRM clinic that uses the ChartNeo app to HFEA (Human Fertilization and Embryology Authority) data, both from 2019. RRM treatment had a live birth rate of 40.4% compared to 24.4% per treatment cycle for IVF (P>0.0001). RRM twin pregnancy rate was 2.5% compared to 7% for IVF. RRM babies were usually full term and normal birth weight. Therefore, RRM is less expensive, less invasive, and more effective than IVF for most patients. This merits further evaluation and support by the HSE and other global authorities guiding health policy.

Keywords

infertility; in-vitro fertilization; assisted reproductive technology; restorative reproductive medicine

Subject

Medicine and Pharmacology, Reproductive Medicine

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