Lala, I.R.; Pop-Moldovan, A. Inflammation—A Possible Link between Myocarditis and Arrhythmogenic Cardiomyopathy. Diagnostics2024, 14, 248.
Lala, I.R.; Pop-Moldovan, A. Inflammation—A Possible Link between Myocarditis and Arrhythmogenic Cardiomyopathy. Diagnostics 2024, 14, 248.
Lala, I.R.; Pop-Moldovan, A. Inflammation—A Possible Link between Myocarditis and Arrhythmogenic Cardiomyopathy. Diagnostics2024, 14, 248.
Lala, I.R.; Pop-Moldovan, A. Inflammation—A Possible Link between Myocarditis and Arrhythmogenic Cardiomyopathy. Diagnostics 2024, 14, 248.
Abstract
Arrhythmogenic cardiomyopathy is a primary genetic disease caused by mutations of the desmosome genes. Ever since the introduction of new imaging criteria, like cardiovascular magnetic resonance, the diagnosis of arrhythmogenic cardiomyopathy is more challenging as left ventricular or biventricular variants may cause resemblance with other cardiomyopathies or myocarditis. Not only this, but they may also share an acute phase that might determine even more confusion and misdiagnosis which can influence prognosis and outcome. In this case report we present a 31-year-old patient with multiple clinical pictures: acute chest pain, new onset of heart failure and arrhythmia symptoms which determined a dynamic change in clinical diagnosis and management, ultimately taking into consideration arrhythmogenic cardiomyopathy. Through the article we try to emerge and explain common pathophysiological pathways shared by arrhythmogenic cardiomyopathy and other clinical entities with a special focus on inflammation. The final question remains: “If there is more than one heart disorder that eventually will lead to the same clinical picture, one could not but wonder if arrhythmogenic cardiomyopathy is rather a syndrome than a specific condition?”
Keywords
inflammation; myocarditis; arrhythmogenic cardiomyopathy; cardiovascular magnetic resonance
Subject
Medicine and Pharmacology, Cardiac and Cardiovascular Systems
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
