Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

EUS-GE in Gastric Outlet Obstruction Management: Current Methods and Comparisons

Dimitrios Ziogas
* ORCID logo ,
Thomas Vasilakis
ORCID logo ,
Christina Kapizioni
,
Eleni Koukoulioti
,
Georgios Tziatzios
ORCID logo ,
Paraskevas Gkolfakis
ORCID logo ,
Antonio Facciorusso
,
Ioannis S. Papanikolaou
ORCID logo
Version 1 : Received: 18 December 2023 / Approved: 19 December 2023 / Online: 19 December 2023 (10:46:59 CET)

A peer-reviewed article of this Preprint also exists.

Ziogas, D.; Vasilakis, T.; Kapizioni, C.; Koukoulioti, E.; Tziatzios, G.; Gkolfakis, P.; Facciorusso, A.; Papanikolaou, I.S. Revealing Insights: A Comprehensive Overview of Gastric Outlet Obstruction Management, with Special Emphasis on EUS-Guided Gastroenterostomy. Med. Sci. 2024, 12, 9. Ziogas, D.; Vasilakis, T.; Kapizioni, C.; Koukoulioti, E.; Tziatzios, G.; Gkolfakis, P.; Facciorusso, A.; Papanikolaou, I.S. Revealing Insights: A Comprehensive Overview of Gastric Outlet Obstruction Management, with Special Emphasis on EUS-Guided Gastroenterostomy. Med. Sci. 2024, 12, 9.

Abstract

Gastric outlet obstruction (GOO) poses a common and challenging clinical scenario, characterized by mechanical blockage in the pylorus, distal stomach, or duodenum, resulting in symptoms such as nausea, vomiting, abdominal pain, and early satiety. Its diverse etiology encompasses both benign and malignant disorders. The spectrum of current treatment modalities extends from conservative approaches to more invasive interventions, incorporating procedures like surgical gastroenterostomy (SGE), self-expandable metallic stents (SEMS) placement, and the advanced technique of endoscopic ultrasound-guided gastroenterostomy (EUS-GE). While surgery is favored for longer life expectancy, stents are preferred in malignant gastric outlet stenosis. The novel EUS-GE technique, employing a lumen-apposing self-expandable metal stent (LAMS), combines the immediate efficacy of stents with the enduring benefits of gastroenterostomy. Despite its promising outcomes, EUS-GE is a technically demanding procedure requiring specialized expertise and facilities.

Keywords

Endoscopic ultrasound-guided gastroenterostomy; Gastric outlet obstruction; Endosonography; Self expandable metal stent; Gastroenterostomy

Subject

Medicine and Pharmacology, Gastroenterology and Hepatology

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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