Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Advancements in Cold Atmospheric Plasma for Skin Disease Treatment and Skincare: A Brief Update

Version 1 : Received: 12 December 2023 / Approved: 13 December 2023 / Online: 13 December 2023 (03:28:04 CET)

How to cite: Khalaf, A.T.; Oglah, Z.; Liu, X. Advancements in Cold Atmospheric Plasma for Skin Disease Treatment and Skincare: A Brief Update. Preprints 2023, 2023120934. https://doi.org/10.20944/preprints202312.0934.v1 Khalaf, A.T.; Oglah, Z.; Liu, X. Advancements in Cold Atmospheric Plasma for Skin Disease Treatment and Skincare: A Brief Update. Preprints 2023, 2023120934. https://doi.org/10.20944/preprints202312.0934.v1

Abstract

Cold atmospheric plasma (CAP) has emerged as a promising therapeutic technology, distinguished by its safety, efficiency, and minimal side effects. With increasing applications in dermatology, CAP demonstrates antimicrobial efficacy against bacteria, viruses, and fungi, supports tissue proliferation and wound healing, and hinders the growth and migration of tumor cells. This review encompasses the concept, physical characteristics, and current research applications of CAP in dermatology. CAP, a gas cloud produced by ionizing gases, operates at room temperature, ensuring safety and efficacy in dermatological use. Its effects are mediated through active components like reactive oxygen and nitrogen species (RONS) and ultraviolet radiation. The extensive research covered in this paper explores CAP's applications in skin infections, immune-related diseases, and tumor diseases. As a biologically suitable technology, cold atmospheric pressure plasma finds widespread use in medicine, including medical device sterilization, dentistry, oncology, and dermatology. The direct and indirect forms of CAP applications, including plasma-activated liquids, complement each other. CAP holds promise as a dermatological treatment technique, but further exploration and research are needed. This article briefly explores CAP's diverse applications and potential utility within dermatology. The objective is to enhance the progress of plasma medicine by furnishing a concise overview of the applications of this groundbreaking technology in dermatological contexts.

Keywords

cold atmospheric plasma; dermatological diseases; skincare

Subject

Medicine and Pharmacology, Medicine and Pharmacology

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