Delusional Misidentification Syndrome in Parkinson’s Dementia Resolved with Rivastigmine

Emile d'Angremont; Johan Berghuis; Iris Sommer

doi:10.20944/preprints202312.0123.v1

Preprint Case Report Version 1 Preserved in Portico This version is not peer-reviewed

Version 1 : Received: 1 December 2023 / Approved: 4 December 2023 / Online: 4 December 2023 (04:27:03 CET)

In advanced Parkinson’s disease (PD), and especially in PD related dementia (PDD), psychotic symptoms are common. One of the manifestations of psychosis in PD is delusional misidentification syndrome, a phenomenon in which the patient believes the identity of a person, object or location has been duplicated or altered. Our patient, a 75-year-old female, was diagnosed with idiopathic Parkinson’s disease at the age of 68. Recently, her cognition deteriorated and she developed the believe that she lived in a replica of her real home. The delusion resolved completely with rivastigmine patches. Also visual hallucinations improved on treatment. This suggests that the dysfunctional connections were likely to be cholinergic.

Capgras syndrome; Delusions; Parkinson disease; Dementia; Cholinesterase Inhibitors

Medicine and Pharmacology, Neuroscience and Neurology

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Delusional Misidentification Syndrome in Parkinson’s Dementia Resolved with Rivastigmine

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