Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Hand-Held Echocardiography by Advanced Practice Providers in Patients with Congestive Heart Failure

Version 1 : Received: 28 November 2023 / Approved: 29 November 2023 / Online: 29 November 2023 (23:04:44 CET)

A peer-reviewed article of this Preprint also exists.

Tagle-Cornell, M.C.; Novais, B.S.; Wen, S.; Shipman, J.N.; Mandale, D.R.; Flom, A.P.; Sahnan, S.K.; Kriz, L.M.; Alland, M.L.; Bird, C.W.; Naqvi, T.Z. Hand-Held Echocardiography by Advanced Practice Providers in Patients with Congestive Heart Failure. J. Clin. Med. 2024, 13, 312. Tagle-Cornell, M.C.; Novais, B.S.; Wen, S.; Shipman, J.N.; Mandale, D.R.; Flom, A.P.; Sahnan, S.K.; Kriz, L.M.; Alland, M.L.; Bird, C.W.; Naqvi, T.Z. Hand-Held Echocardiography by Advanced Practice Providers in Patients with Congestive Heart Failure. J. Clin. Med. 2024, 13, 312.

Abstract

Objectives: Evaluate hand-held echocardiography (HHE) performed and interpreted by trained Advanced Practice Providers (APPs) on hospitalized CHF patients for image quality and interpretation, by comparing against expert echocardiographer and SE findings. Background: Congestive heart failure (CHF) is associated with increased hospital admissions and mortality. While standard echocardiogram (SE) is the gold standard for cardiac assessment, it is not readily available. Hospitalized CHF patients require rapid assessment for expedited treatment. Methods: Over 6 months, five trained APPs performed HHE on hospitalized CHF patients and interpreted: a) Left ventricular (LV) size, b) LV ejection fraction (LVEF), and c) right atrial pressure (RAP). The study echocardiographer reviewed and blindly interpreted HHE images and compared with APPs and SE findings. Kappa-statistics determined the degree of agreement between APPs and study echocardiographer interpretation of HHE images and SE. Results: 80 CHF patients [age 73±14 years, 58% males; LVEF (by SE) 45±19%; 36.3% body mass indexes ≥30 kg/m2] were enrolled. HHE interpretation by APPs had good agreement for LVEF (kappa 0.79) with study echocardiographer and SE (kappa 0.74), and good agreement for RAP (kappa 0.67) with study echocardiographer. Correlation between absolute LVEF interpretation by study echocardiographer on HHE and SE was r=0.88 (p<0.0001). Conclusions: Trained APPs obtained diagnostic-quality HHE images and interpreted LV function and RAP in CHF patients, with good agreement with the study echocardiographer. LVEF by HHE correlated with LVEF by SE. Our study suggests trained APPs can use HHE to evaluate LVEF and RAP in CHF patients leading to expedited and optimized treatment.

Keywords

Congestive heart failure; echocardiography; hand-held echocardiogram; heart failure; images, advanced practice providers

Subject

Medicine and Pharmacology, Cardiac and Cardiovascular Systems

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