Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Biosynthesis of Gamma-AminoButyric Acid (GABA) by Lactiplantibacillus plantarum in Fermented Food Production

Version 1 : Received: 28 November 2023 / Approved: 29 November 2023 / Online: 29 November 2023 (06:14:14 CET)

A peer-reviewed article of this Preprint also exists.

Iorizzo, M.; Paventi, G.; Martino, C.D. Biosynthesis of Gamma-Aminobutyric Acid (GABA) by Lactiplantibacillus plantarum in Fermented Food Production. Curr. Issues Mol. Biol. 2024, 46, 200-220. Iorizzo, M.; Paventi, G.; Martino, C.D. Biosynthesis of Gamma-Aminobutyric Acid (GABA) by Lactiplantibacillus plantarum in Fermented Food Production. Curr. Issues Mol. Biol. 2024, 46, 200-220.

Abstract

In recent decades, given the important role of gamma-aminobutyric acid (GABA) in human health, scientists have paid great attention to the enrichment of this chemical compound in food using various methods, including microbial fermentation. Moreover, GABA or GABA-rich products have been successfully commercialized as food additives or functional dietary supplements. Several microorganisms can produce GABA, including bacteria, fungi, and yeasts. Among GABA-producing bacteria, lactic acid bacteria (LAB) are commonly used in the production of many fermented foods. Lactiplantibacillus plantarum (previously Lactobacillus plantarum) has a long history of natural occurrence and safe use in a variety of food products. This LAB species provides functional properties to various fermented foods by producing a variety of bioactive compounds, including GABA. The present review aims, after a preliminary excursus on the function and biosynthesis of GABA, to provide an overview on the current uses of microorganisms and in particular of L. plantarum in the production of GABA, with a detailed focus on fermented foods.

Keywords

lactobacillus plantarum; functional food; L-glutamate decarboxylase; lactic acid bacteria

Subject

Biology and Life Sciences, Food Science and Technology

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