Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Recent Advances in Understanding COVID-19 Pathophysiology and Therapy: A Review

Version 1 : Received: 25 November 2023 / Approved: 28 November 2023 / Online: 30 November 2023 (10:45:53 CET)

How to cite: Rangraze, I.; Jhancy, M.; Khan, S. Recent Advances in Understanding COVID-19 Pathophysiology and Therapy: A Review. Preprints 2023, 2023111743. https://doi.org/10.20944/preprints202311.1743.v1 Rangraze, I.; Jhancy, M.; Khan, S. Recent Advances in Understanding COVID-19 Pathophysiology and Therapy: A Review. Preprints 2023, 2023111743. https://doi.org/10.20944/preprints202311.1743.v1

Abstract

For over two years, the global COVID-19 pandemic has persisted, and its continuation is anticipated. The emergence and rapid spread of numerous new virus variations across continents have been observed. These variants, differing from previously known strains, manifest a spectrum of behaviors and clinical presentations, ranging from asymptomatic cases to severe illnesses and fatalities. Despite substantial research efforts in recent years, significant uncertainties persist in understanding the disease, encompassing variations in clinical outcomes, comorbidities, and challenges faced by individuals infected with COVID-19. Beyond the acute phase of infection, the prevalence of post-COVID-19 symptoms, often denoted as "long COVID," is notable, particularly in individuals recovering from the disease. Nevertheless, a research gap persists concerning the pathophysiological mechanisms underlying newly emerging viral variant infections, post-COVID-19 conditions, and the corresponding therapeutic strategies. This review is presented to analyze recent advancements in comprehending the pathophysiology and therapy of COVID-19.

Keywords

COVID 19; recent advances; pathophysiology; therapy

Subject

Medicine and Pharmacology, Epidemiology and Infectious Diseases

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