Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Gender-specific Dimensional Shape Analysis of Carpal Bones: Implications for Biomedical Device Design and Therapy Planning

Version 1 : Received: 6 November 2023 / Approved: 6 November 2023 / Online: 6 November 2023 (15:09:35 CET)

A peer-reviewed article of this Preprint also exists.

Asseln, M.; Quack, V.; Michalik, R.; Rath, B.; Hildebrand, F.; Migliorini, F.; Eschweiler, J. Sex-Specific Size Analysis of Carpal Bones: Implications for Orthopedic Biomedical Device Design and Therapy Planning. Life 2024, 14, 140. Asseln, M.; Quack, V.; Michalik, R.; Rath, B.; Hildebrand, F.; Migliorini, F.; Eschweiler, J. Sex-Specific Size Analysis of Carpal Bones: Implications for Orthopedic Biomedical Device Design and Therapy Planning. Life 2024, 14, 140.

Abstract

Consideration of the individual bone characteristics of the wrist plays a key role in well-functioning biomedical devices and successful surgical procedures. Although geometric differences and individual bone sizes have been analyzed in the literature, detailed morphologic descriptions and correlations covering the entire wrist reported in a clinical context are lacking. This study aimed to perform a comprehensive and automatic analysis of wrist morphology using the freely available “Open Source Carpal Database” (OSCD). We quantified the dimensions of each of the individual carpal bones and their combination. These dimensions were extracted in n=117 datasets of the wrist of the OSCD in anatomical directions and analyzed using descriptive statics and correlation analysis to investigate morphological characteristics under gender-specific aspects. We found that there exist statistical differences between genders, and we concluded that gender specificity is an important variable affecting the utilization of biomedical device designs and clinical treatment.

Keywords

wrist; morphology; biomedical device design; therapy planning; biomechanics

Subject

Medicine and Pharmacology, Anatomy and Physiology

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