Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Comorbidity of Type 2 Diabetes and Dementia Among Hospitalized Patients in Los Angeles County, 2019-2021

Version 1 : Received: 12 October 2023 / Approved: 13 October 2023 / Online: 13 October 2023 (08:26:02 CEST)

A peer-reviewed article of this Preprint also exists.

Robinson, D.M.; Regos-Stewart, D.; Reyes, M.A.; Kuo, T.; Barragan, N.C. Comorbidity of Type 2 Diabetes and Dementia among Hospitalized Patients in Los Angeles County: Hospitalization Outcomes and Costs, 2019–2021. Diabetology 2023, 4, 586-599. Robinson, D.M.; Regos-Stewart, D.; Reyes, M.A.; Kuo, T.; Barragan, N.C. Comorbidity of Type 2 Diabetes and Dementia among Hospitalized Patients in Los Angeles County: Hospitalization Outcomes and Costs, 2019–2021. Diabetology 2023, 4, 586-599.

Abstract

Hospitalizations for patients with diabetes and dementia take a significant health and economic toll on older adults in the United States. The present study sought to examine the differences in hospitalization characteristics and outcomes associated with diabetes and dementia separately and together using discharge record data of Los Angeles County residents aged 50+ from the California Department of Health Care Access and Information for the period 2019-2021. Results from multiple linear regression analyses indicated that when compared to those with no diabetes or dementia, patients with diabetes alone exhibited the highest total charges, while those with comorbid diabetes and dementia exhibited lower charges (p≤.05). Results of a multinomial logistic regression found that patients with comorbid diabetes and dementia had the highest odds of having a length of stay of 7+ days (AOR=1.49; 95% CI=1.44-1.53). A matched-case control analysis found that comorbid diabetes and dementia was associated with significantly lower odds of hypertensive disease than diabetes alone (MOR=0.81; 95% CI=0.67-0.97). These results highlight the complexity of factors affecting variation in hospitalization outcomes across these distinct disease profiles. Findings suggest a need to carefully consider this complexity when developing health policies or strategies to improve hospitalization outcomes involving these disease conditions.

Keywords

diabetes; Alzheimer’s disease; dementia; hospitalization

Subject

Public Health and Healthcare, Public Health and Health Services

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