Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Clinical Features of Hospitalized Stroke Patients Infected with SARS-CoV-2 Omicron Variant

Hiroshi Kanno
* ORCID logo ,
Kazuki Miyazaki
,
Sachiko Yamada
,
Shutaro Matsumoto
,
Yuki Sagehashi
,
Satoru Takahashi
,
Yongson Kim
,
Keiko Namiki
,
Satoshi Fujii
Version 1 : Received: 5 October 2023 / Approved: 5 October 2023 / Online: 9 October 2023 (09:30:50 CEST)

How to cite: Kanno, H.; Miyazaki, K.; Yamada, S.; Matsumoto, S.; Sagehashi, Y.; Takahashi, S.; Kim, Y.; Namiki, K.; Fujii, S. Clinical Features of Hospitalized Stroke Patients Infected with SARS-CoV-2 Omicron Variant. Preprints 2023, 2023100409. https://doi.org/10.20944/preprints202310.0409.v1 Kanno, H.; Miyazaki, K.; Yamada, S.; Matsumoto, S.; Sagehashi, Y.; Takahashi, S.; Kim, Y.; Namiki, K.; Fujii, S. Clinical Features of Hospitalized Stroke Patients Infected with SARS-CoV-2 Omicron Variant. Preprints 2023, 2023100409. https://doi.org/10.20944/preprints202310.0409.v1

Abstract

COVID-19 has rapidly spread worldwide since December 2019. During the pandemic, SARS-CoV-2 repeatedly mutated from Alpha to Omicron. The severity and mortality are related to age, sex, and underlying diseases (respiratory, cerebrovascular, cardiovascular, metabolic, cancer, and immune diseases). We retrospectively studied 44 hospitalized stroke patients infected with the SARS-CoV-2 Omicron variant. The mortality rate of hospitalized stroke patients with COVID-19 was 6 (13.6%). The cause of death was coagulopathy in 3 cases of ischemic stroke. High modified Rankin Scale score（mRS）of stroke patient was correlated with severity of COVID-19. The timing of vaccination is inversely correlated with COVID-19 severity. In conclusion, stroke patients with COVID-19 have high mortality rates attributed to coagulopathy. Stroke patients with high mRS scores are more likely to develop severe COVID-19. In high mRS scores, therapy for severe COVID-19 should be administered.

Keywords

Stroke; COVID-19; SARS-CoV-2 Omicron variant; modified Ranking scale; coagulopathy

Subject

Medicine and Pharmacology, Clinical Medicine

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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