PreprintArticleVersion 1Preserved in Portico This version is not peer-reviewed
SARS-CoV-2 phoenix: Empirical formulas and thermodynamic properties (enthalpy, entropy and Gibbs energy) of nucleocapsid, virus particle and biosynthesis of BA.2.86 Pirola variant
Version 1
: Received: 27 September 2023 / Approved: 28 September 2023 / Online: 28 September 2023 (11:23:34 CEST)
How to cite:
Popović, M. E.; Šekularac, G.; Popović, M. SARS-CoV-2 phoenix: Empirical formulas and thermodynamic properties (enthalpy, entropy and Gibbs energy) of nucleocapsid, virus particle and biosynthesis of BA.2.86 Pirola variant. Preprints2023, 2023091964. https://doi.org/10.20944/preprints202309.1964.v1
Popović, M. E.; Šekularac, G.; Popović, M. SARS-CoV-2 phoenix: Empirical formulas and thermodynamic properties (enthalpy, entropy and Gibbs energy) of nucleocapsid, virus particle and biosynthesis of BA.2.86 Pirola variant. Preprints 2023, 2023091964. https://doi.org/10.20944/preprints202309.1964.v1
Popović, M. E.; Šekularac, G.; Popović, M. SARS-CoV-2 phoenix: Empirical formulas and thermodynamic properties (enthalpy, entropy and Gibbs energy) of nucleocapsid, virus particle and biosynthesis of BA.2.86 Pirola variant. Preprints2023, 2023091964. https://doi.org/10.20944/preprints202309.1964.v1
APA Style
Popović, M. E., Šekularac, G., & Popović, M. (2023). SARS-CoV-2 phoenix: Empirical formulas and thermodynamic properties (enthalpy, entropy and Gibbs energy) of nucleocapsid, virus particle and biosynthesis of BA.2.86 Pirola variant. Preprints. https://doi.org/10.20944/preprints202309.1964.v1
Chicago/Turabian Style
Popović, M. E., Gavrilo Šekularac and Marta Popović. 2023 "SARS-CoV-2 phoenix: Empirical formulas and thermodynamic properties (enthalpy, entropy and Gibbs energy) of nucleocapsid, virus particle and biosynthesis of BA.2.86 Pirola variant" Preprints. https://doi.org/10.20944/preprints202309.1964.v1
Abstract
Similarly to a phoenix, SARS-CoV-2 has appeared periodically in waves. The new variants that appeared through mutations have during the 4 years of the pandemic suppressed earlier variants, causing new waves of the pandemic. The Omicron BA.2.86 Pirola variant is the latest in the sequence of SARS-CoV-2 variants, which appeared in 2023. The BA.2.86 variant has started to spread rapidly and we are witnesses of a new epidemic wave. In this short period, an increased infectivity was noticed, which results in rapid spreading and decreased pathogenicity, which results in a lower number of severe cases. However, in the public there is a fear of further development of the epidemic. This analysis was made with the goal to assess the risks in the period of late 2023. Mutations that were developed by the BA.2.86 variant have led to a change in empirical formula and thermodynamic properties. It seems that there is no ground for fear of an extensive spreading of severe forms, but there are reasons for caution and monitoring of the spreading of the epidemic and potential appearance of new mutations.
Keywords
Biothermodynamics; Virus-host interaction; COVID-19; Pandemic; Variant under monitoring; Pathogenicity; Pathogen; August 2023
Subject
Biology and Life Sciences, Virology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
